(R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate

Base Information

• Chemical Name: (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate
• CAS No.: 1312997-75-3
• Molecular Formula: C₁₆H₁₅ClO₅
• Molecular Weight: 322.745
• Mol file: 1312997-75-3.mol

Synonyms:(R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate

Chemical Property of (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate

There total 8 articles about (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + 2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate (1312997-67-3) → (S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate (1312997-71-9) + (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate (1312997-75-3)

Guidance literature:

With Pseudomonas fluorescens lipase AK; In di-isopropyl ether; at 20 ℃; optical yield given as %ee; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.03.006

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + 1-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate (1312997-63-9) → (S)-1-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate + (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate (1312997-75-3)

Guidance literature:

With Burkholderia cepacia lipase; In di-isopropyl ether; at 20 ℃; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.03.006

Reference yield:

1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate (1312997-59-3) → (S)-1-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate + (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate (1312997-75-3)

Guidance literature:

With methanol; at 20 ℃; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.03.006

upstream raw materials:

vinyl acetate

1-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

1-(5-(2-chlorophenyl)furan-2-yl)ethanone

Downstream raw materials:

(R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diol