(S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

Base Information

• Chemical Name: (S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate
• CAS No.: 1312997-71-9
• Molecular Formula: C₁₄H₁₃ClO₄
• Molecular Weight: 280.708
• Mol file: 1312997-71-9.mol

Synonyms:(S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

Chemical Property of (S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

There total 1 articles about (S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + 2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate (1312997-67-3) → (S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate (1312997-71-9) + (R)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diyl diacetate (1312997-75-3)

Guidance literature:

With Pseudomonas fluorescens lipase AK; In di-isopropyl ether; at 20 ℃; optical yield given as %ee; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.03.006

Reference yield:

(S)-2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate (1312997-71-9) → (S)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diol (1225302-35-1)

Guidance literature:

With Burkholderia cepacia lipase; water; In methanol; di-isopropyl ether; at 20 ℃; for 12h; pH=7.5; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.03.006

upstream raw materials:

vinyl acetate

2-(5-(2-chlorophenyl)furan-2-yl)-2-hydroxyethyl acetate

Downstream raw materials:

(S)-1-(5-(2-chlorophenyl)furan-2-yl)ethane-1,2-diol