N1-ethyl-4-methoxybenzene-1,2-diamine

Base Information

Chemical Name:N1-ethyl-4-methoxybenzene-1,2-diamine
CAS No.:79938-45-7
Molecular Formula:C₉H₁₄N₂O
Molecular Weight:166.223
Hs Code.:
DSSTox Substance ID:DTXSID701288684

Synonyms:79938-45-7;N1-ethyl-4-methoxybenzene-1,2-diamine;1,2-Benzenediamine, N1-ethyl-4-methoxy-;SCHEMBL8348984;DTXSID701288684;AKOS017532268;N1-Ethyl-4-methoxy-1,2-benzenediamine;1-N-ethyl-4-methoxybenzene-1,2-diamine

Suppliers and Price of N1-ethyl-4-methoxybenzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N1-ethyl-4-methoxybenzene-1,2-diamine

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:166.110613074
Heavy Atom Count:12
Complexity:130

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCNC1=C(C=C(C=C1)OC)N

Technology Process of N1-ethyl-4-methoxybenzene-1,2-diamine

There total 4 articles about N1-ethyl-4-methoxybenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3360-85-8
N-ethyl-(4-methoxy-2-nitrophenyl)amine

: 79938-45-7
4-methoxy-N¹-ethylbenzene-1,2-diamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 4h; under 2280 Torr; Yield given; Ambient temperature;

Reference yield:

: 96-96-8
4-methoxy-2-nitroaniline

: 79938-45-7
4-methoxy-N¹-ethylbenzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / sodium cyanoborohydride / methanol; tetrahydrofuran; acetic acid / 50 °C / pH: 5 - 5.5

2: hydrogen / Pd/charcoal / methanol / 4 h / 2280 Torr / Ambient temperature

With hydrogen; sodium cyanoborohydride; palladium on activated charcoal; In tetrahydrofuran; methanol; acetic acid;

Reference yield:

: 61324-93-4
1-fluoro-nitro-4-methoxybenzene

: 79938-45-7
4-methoxy-N¹-ethylbenzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 12 h / Sealed tube

2: sodium dithionite / tetrahydrofuran; water; ethanol / 4 h / 0 - 20 °C

With sodium dithionite; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b00274