ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

Base Information

Chemical Name:ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate
CAS No.:1332461-98-9
Molecular Formula:C₂₁H₂₄F₃NO₃
Molecular Weight:395.422
Hs Code.:

Synonyms:ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

Suppliers and Price of ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

There total 2 articles about ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1258209-32-3
C₁₄H₁₆F₃NO₃

: C₇H₇ClZn*Cl₃LiMg

: 1332461-98-9
ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

Guidance literature:: C₁₄H₁₆F₃NO₃; C₇H₇ClZn*Cl₃LiMg; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; optical yield given as %de; diastereoselective reaction;
DOI:10.1016/j.tetlet.2011.07.006

Reference yield:

: 1258209-32-3
C₁₄H₁₆F₃NO₃

: C₇H₇ClZn*Cl₃LiMg

: ethyl 2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

: 1332461-98-9
ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

Guidance literature:: In tetrahydrofuran; at 25 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.07.006

Reference yield: 99.0%

: 1332461-98-9
ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate

: 1332462-08-4
(S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoic acid

Guidance literature:: ethyl (S)-2-benzyl-3,3,3-trifluoro-2-(((R)-2-methoxy-1-phenylethyl)amino)propanoate; With potassium hydroxide; In methanol; water; at 20 ℃; for 36h;

With hydrogenchloride; water; In methanol; pH=1 - 2;
DOI:10.1016/j.tetlet.2011.07.006