Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate

Base Information

Chemical Name:Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate
CAS No.:137255-86-8
Molecular Formula:C₂₁H₂₅NO₄
Molecular Weight:355.434
Hs Code.:2924299090
DSSTox Substance ID:DTXSID90371635,DTXSID101145022
Mol file:137255-86-8.mol

Synonyms:Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate;Methyl 3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate;SCHEMBL2802961;DTXSID90371635;XJFJKCSCNLXBCY-UHFFFAOYSA-N;DTXSID101145022;AB20916;Y13866;t-butoxycarbonylamino-3-(biphenyl-4-yl)-propionic acid methyl ester;Methyl alpha-[[(1,1-dimethylethoxy)carbonyl]amino][1,1'-biphenyl]-4-propanoate;169885-20-5

Suppliers and Price of Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(S)-Methyl N-tert-butoxycarbonyl-3-(4-biphenylyl)-2-aminopropionate 98%
5 g
$ 2800.00

Crysdot
(S)-Methyl3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate 95+%
10g
$ 1067.00

Crysdot
(S)-Methyl3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate 95+%
5g
$ 760.00

American Custom Chemicals Corporation
(S)-METHYL N-TERT-BUTOXYCARBONYL-3-(4-BIPHENYLYL)-2-AMINOPROPIONATE 95.00%
250MG
$ 704.11

Alichem
(S)-Methyl3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate
25g
$ 1146.08

Alichem
(S)-Methyl3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate
10g
$ 875.16

Alichem
(S)-Methyl3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate
5g
$ 648.72

Total 16 raw suppliers

Chemical Property of Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.538
Boiling Point:508.6 °C at 760 mmHg
Flash Point:261.4 °C
PSA：64.63000
Density:1.113 g/cm³
LogP:4.35330
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:355.17835828
Heavy Atom Count:26
Complexity:457

Purity/Quality:

99%, ^*data from raw suppliers

(S)-Methyl N-tert-butoxycarbonyl-3-(4-biphenylyl)-2-aminopropionate 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)C2=CC=CC=C2)C(=O)OC

Technology Process of Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate

There total 9 articles about Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 112766-18-4
methyl N-(tert-butoxycarbonyl)-O-[(trifluoromethyl)sulfonyl]-L-tyrosinate

: 98-80-6
phenylboronic acid

: 137255-86-8
methyl (S)-3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 85 - 90 ℃; for 2h; Product distribution; other arylboronic acids;
DOI:10.1021/jo00027a066

Reference yield: 91.0%

: 113850-76-3,210962-91-7
N-(tert-butoxycarbonyl)-4-iodo-L-phenylalanine methyl ester

: 98-80-6
phenylboronic acid

: 137255-86-8
methyl (S)-3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; toluene;
DOI:10.1016/S0960-894X(01)00582-0

Reference yield: 81.0%

: 591-50-4
iodobenzene

: methyl N-tert-butyloxycarbonyl-L-(4-trimethylstannylphenyl)alaninate

: 137255-86-8
methyl (S)-3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoate

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triphenyl-arsane; In N,N-dimethyl-formamide; at 60 ℃; for 2h;
DOI:10.1055/s-0030-1260179