C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide

Base Information

Chemical Name:C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide
CAS No.:1376372-17-6
Molecular Formula:C₁₇H₁₆BrF₂NO₂S
Molecular Weight:416.286
Hs Code.:

Synonyms:C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide

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Chemical Property of C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide

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Technology Process of C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide

There total 2 articles about C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1178830-06-2
(4-bromo-2-fluorophenyl)methanesulphonyl chloride

: 75180-46-0
(1-(4-fluorophenyl)cyclopropyl)methanamine

: 1376372-17-6
C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide

Guidance literature:: (4-bromo-2-fluorophenyl)methanesulphonyl chloride; (1-(4-fluorophenyl)cyclopropyl)methanamine; With triethylamine; In acetonitrile; at 20 ℃; Combinatorial reaction / High throughput screening (HTS); Sealed tube;

In acetonitrile; at 80 ℃; for 2h; Combinatorial reaction / High throughput screening (HTS); Sealed tube; Sonication;
DOI:10.1021/co400164z

Reference yield: 70.0%

: 75180-46-0
(1-(4-fluorophenyl)cyclopropyl)methanamine

: 1240528-68-0
C₇H₅BrF₂O₂S

: 1376372-17-6
C-(4-bromo-2-fluorophenyl)-N-[1-(4-fluorophenyl)-cyclopropylmethyl]methanesulfonamide

Guidance literature:: (1-(4-fluorophenyl)cyclopropyl)methanamine; C₇H₅BrF₂O₂S; With triethylamine; In acetonitrile; at 20 ℃; Combinatorial reaction / High throughput screening (HTS); Sealed tube;

In acetonitrile; at 80 ℃; for 4h; Combinatorial reaction / High throughput screening (HTS); Sealed tube; Sonication;
DOI:10.1021/co400164z