[1-(4-Fluorophenyl)cyclopropyl]methanamine

Base Information

Chemical Name:[1-(4-Fluorophenyl)cyclopropyl]methanamine
CAS No.:75180-46-0
Molecular Formula:C10H12FN
Molecular Weight:165.21
Hs Code.:2921499090
European Community (EC) Number:840-935-9
DSSTox Substance ID:DTXSID40602562
Wikidata:Q82499688
Mol file:75180-46-0.mol

Synonyms:75180-46-0;[1-(4-fluorophenyl)cyclopropyl]methanamine;1-(4-fluorophenyl)Cyclopropanemethanamine;(1-(4-fluorophenyl)cyclopropyl)methanamine;1-[1-(4-fluorophenyl)cyclopropyl]methanamine;1-(4-FLUOROPHENYL)-CYCLOPROPANEMETHANAMINE;SCHEMBL1672596;DTXSID40602562;LIZUFNBWJGVYRB-UHFFFAOYSA-N;MFCD06213570;AKOS000345260;AB23420;SY174881;DB-074952;CS-0249141;EN300-42604;VU0494887-1;C78439;A915199;C-[1-(4-FLUORO-PHENYL)-CYCLOPROPYL]-METHYLAMINE;F2189-0509;Z361884280

Suppliers and Price of [1-(4-Fluorophenyl)cyclopropyl]methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Fluorophenyl)-cyclopropanemethanamine
50mg
$ 45.00

Anichem
C-[1-(4-Fluoro-phenyl)-cyclopropyl]-methylamine >95%
1g
$ 350.00

American Custom Chemicals Corporation
[1-(4-FLUOROPHENYL)CYCLOPROPYL]METHANAMINE 95.00%
5G
$ 2181.31

American Custom Chemicals Corporation
[1-(4-FLUOROPHENYL)CYCLOPROPYL]METHANAMINE 95.00%
2.5G
$ 1635.30

American Custom Chemicals Corporation
[1-(4-FLUOROPHENYL)CYCLOPROPYL]METHANAMINE 95.00%
1G
$ 1070.84

AK Scientific
[1-(4-Fluorophenyl)cyclopropyl]methanamine
5g
$ 917.00

ACHEMBLOCK
1-(4-Fluorophenyl)-cyclopropanemethanamine 95%
250MG
$ 180.00

ACHEMBLOCK
1-(4-Fluorophenyl)-cyclopropanemethanamine 95%
1G
$ 370.00

Total 10 raw suppliers

Chemical Property of [1-(4-Fluorophenyl)cyclopropyl]methanamine

Chemical Property:

Boiling Point:232.7±23.0 °C(Predicted)
PKA:10.36±0.29(Predicted)
PSA：26.02000
Density:1.140±0.06 g/cm3(Predicted)
LogP:2.51630
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:165.095377549
Heavy Atom Count:12
Complexity:157

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Fluorophenyl)-cyclopropanemethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1(CN)C2=CC=C(C=C2)F

Technology Process of [1-(4-Fluorophenyl)cyclopropyl]methanamine

There total 6 articles about [1-(4-Fluorophenyl)cyclopropyl]methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 133284-48-7
1-(4-fluorophenyl)cyclopropane-1-carboxamide

: 75180-46-0
(1-(4-fluorophenyl)cyclopropyl)methanamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 1h; Reflux;

Reference yield:

: 97009-67-1
1-(4-fluorophenyl)cyclopropane-1-carbonitrile

: 75180-46-0
(1-(4-fluorophenyl)cyclopropyl)methanamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.5b02557

Reference yield:

: 1455028-72-4
N-(2,4-dimethoxybenzyl)-1-(4-fluorophenyl)cyclopropanecarboxamide

: 75180-46-0
(1-(4-fluorophenyl)cyclopropyl)methanamine

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / 2 h / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 20 °C / Reflux

With lithium aluminium tetrahydride; trifluoroacetic acid; In tetrahydrofuran;