dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate

Base Information

• Chemical Name: dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate
• CAS No.: 1312150-25-6
• Molecular Formula: C₁₆H₂₀O₄
• Molecular Weight: 276.332
• Mol file: 1312150-25-6.mol

Synonyms:dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate

Chemical Property of dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate

There total 1 articles about dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + methyl chloroformate (79-22-1) + cyclohexanecarbaldehyde (2043-61-0) → dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate (1312150-25-6)

Guidance literature:

cyclopenta-1,3-diene; With sodium; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

methyl chloroformate; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;

cyclohexanecarbaldehyde; Further stages;

DOI:10.1016/j.tet.2011.03.094

Reference yield:

dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate (1312150-25-6) + methyllithium (917-54-4) → dimethyl 3-(1-cyclohexylethyl)cyclopenta-1,3-diene-1,2-dicarboxylate sodium salt

Guidance literature:

methyllithium; With copper(l) iodide; In diethyl ether; at -10 ℃; for 1h; Inert atmosphere;

dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate; In diethyl ether; at -30 ℃; for 0.25h; Further stages; Inert atmosphere;

DOI:10.1016/j.tet.2011.03.094

Reference yield:

dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate (1312150-25-6) + methyllithium (917-54-4) + benzylidene phenylamine (538-51-2) → (E)-dimethyl 5-benzylidene-3-(1-cyclohexylethyl)cyclopenta-1,3-diene-1,2-dicarboxylate (1312150-42-7)

Guidance literature:

methyllithium; With copper(l) iodide; In diethyl ether; at -10 ℃; for 1h; Inert atmosphere;

dimethyl 5-(cyclohexylmethylene)cyclopenta-1,3-diene-1,2-dicarboxylate; In diethyl ether; at -30 ℃; for 0.25h; Inert atmosphere;

benzylidene phenylamine; Further stages;

DOI:10.1016/j.tet.2011.03.094

upstream raw materials:

cyclopenta-1,3-diene

methyl chloroformate

cyclohexanecarbaldehyde

Downstream raw materials:

N-benzylidenebutan-1-amine

(E)-dimethyl 5-benzylidene-3-(1-cyclohexylethyl)cyclopenta-1,3-diene-1,2-dicarboxylate