4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)-

Base Information

Chemical Name:4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)-
CAS No.:52346-11-9
Molecular Formula:C₁₃H₂₃NO₂
Molecular Weight:225.331
Hs Code.:
European Community (EC) Number:610-827-4
DSSTox Substance ID:DTXSID101205646
Nikkaji Number:J2.972.558F

Synonyms:52346-11-9;4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)-;SCHEMBL10354008;DTXSID101205646;EN300-6762604;tert-butyl 2-[(3R,4S)-3-ethenylpiperidin-4-yl]acetate;1,1-Dimethylethyl (3R,4S)-3-ethenyl-4-piperidineacetate

Suppliers and Price of 4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)-

Chemical Property:

Vapor Pressure:0.00191mmHg at 25°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:225.172878976
Heavy Atom Count:16
Complexity:255

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CC1CCNCC1C=C
Isomeric SMILES:CC(C)(C)OC(=O)C[C@@H]1CCNC[C@@H]1C=C

Technology Process of 4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)-

There total 7 articles about 4-Piperidineacetic acid, 3-ethenyl-, 1,1-dimethylethyl ester, (3R,4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 865-47-4
potassium tert-butylate

: 84-31-1
quininone

: 52346-11-9
tert-butyl 2-[(3R,4S)-3-ethenylpiperidin-4-yl]acetate

Guidance literature:: potassium tert-butylate; With oxygen; In tetrahydrofuran; tert-butyl alcohol; for 0.25h; Cooling with ice;

quininone; In tetrahydrofuran; tert-butyl alcohol; at 20 - 35 ℃; for 1.66667h;
DOI:10.15227/orgsyn.075.0223

Reference yield: 60.0%

: 84-31-1
quininone

: 75-65-0
tert-butyl alcohol

: 52346-11-9
tert-butyl 2-[(3R,4S)-3-ethenylpiperidin-4-yl]acetate

Guidance literature:: With potassium tert-butylate; oxygen; In tetrahydrofuran; at 0 ℃; for 0.666667h;
DOI:10.1021/ol2012567

Reference yield:

: 865-47-4
potassium tert-butylate

: 130-95-0
Quinine

: 52346-11-9
tert-butyl 2-[(3R,4S)-3-ethenylpiperidin-4-yl]acetate

Guidance literature:: Quinine; With benzophenone; potassium tert-butylate; In toluene; Inert atmosphere; Reflux;

potassium tert-butylate; With oxygen; In tetrahydrofuran; tert-butyl alcohol; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2017.07.016