[4-(Piperidin-1-ylmethyl)phenyl]methanol

Base Information

Chemical Name:[4-(Piperidin-1-ylmethyl)phenyl]methanol
CAS No.:91271-62-4
Molecular Formula:C13H19NO
Molecular Weight:205.3
Hs Code.:2933399090
European Community (EC) Number:640-685-9
DSSTox Substance ID:DTXSID10428135
Wikidata:Q82240922
Mol file:91271-62-4.mol

Synonyms:[4-(piperidin-1-ylmethyl)phenyl]methanol;91271-62-4;(4-(Piperidin-1-ylmethyl)phenyl)methanol;{4-[(piperidin-1-yl)methyl]phenyl}methanol;4-[(Piperidin-1-yl)methyl]benzyl alcohol;SCHEMBL2249251;DTXSID10428135;TQR0097;MFCD07772863;AKOS000320969;4-(1-Piperidinylmethyl)benzenemethanol;PS-5813;SB43105;Benzenemethanol,4-(1-piperidinylmethyl)-;CS-0206494;FT-0752580;EN300-252659;F81811

Suppliers and Price of [4-(Piperidin-1-ylmethyl)phenyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[4-(Piperidin-1-ylmethyl)phenyl]methanol
50mg
$ 90.00

TRC
[4-(Piperidin-1-ylmethyl)phenyl]methanol
10mg
$ 45.00

SynQuest Laboratories
4-[(Piperidin-1-yl)methyl]benzyl alcohol
1 g
$ 128.00

Total 8 raw suppliers

Chemical Property of [4-(Piperidin-1-ylmethyl)phenyl]methanol

Chemical Property:

Vapor Pressure:9.22E-05mmHg at 25°C
Refractive Index:1.57
Boiling Point:325.7 °C at 760 mmHg
PKA:14.44±0.10(Predicted)
Flash Point:152.1 °C
PSA：23.47000
Density:1.082 g/cm³
LogP:2.10270
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:169

Purity/Quality:

98%min ^*data from raw suppliers

[4-(Piperidin-1-ylmethyl)phenyl]methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CC2=CC=C(C=C2)CO

Technology Process of [4-(Piperidin-1-ylmethyl)phenyl]methanol

There total 6 articles about [4-(Piperidin-1-ylmethyl)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 68453-37-2
4-(piperidinomethyl)benzoic acid methyl ester

: 91271-62-4
(4-(piperidin-1-ylmethyl)phenyl)methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; Cooling with ice;
DOI:10.1021/acschemneuro.5b00121

Reference yield:

: 110-89-4
piperidine

: 91271-62-4
(4-(piperidin-1-ylmethyl)phenyl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: titanium(IV) isopropoxide / methanol / 3 h / 20 °C

1.2: 65 percent / sodium cyanoborohydride / methanol

2.1: 82 percent / sodium borohydride; AlCl₃ / bis-(2-methoxy-ethyl) ether / 24 h / Heating

With titanium(IV) isopropylate; sodium tetrahydroborate; aluminium trichloride; In methanol; diethylene glycol dimethyl ether;
DOI:10.1021/jm021084k

Reference yield:

: 1571-08-0
methyl 4-formylbenzoate

: 91271-62-4
(4-(piperidin-1-ylmethyl)phenyl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: titanium(IV) isopropoxide / methanol / 3 h / 20 °C

1.2: 65 percent / sodium cyanoborohydride / methanol

2.1: 82 percent / sodium borohydride; AlCl₃ / bis-(2-methoxy-ethyl) ether / 24 h / Heating

With titanium(IV) isopropylate; sodium tetrahydroborate; aluminium trichloride; In methanol; diethylene glycol dimethyl ether;
DOI:10.1021/jm021084k