(4-(3-Oxocyclobutyl)phenyl)boronic acid

Base Information

Chemical Name:(4-(3-Oxocyclobutyl)phenyl)boronic acid
CAS No.:254893-03-3
Molecular Formula:C10H11BO3
Molecular Weight:190
Hs Code.:2931900090
DSSTox Substance ID:DTXSID20400705
Wikidata:Q82203723
Mol file:254893-03-3.mol

Synonyms:(4-(3-Oxocyclobutyl)phenyl)boronic acid;254893-03-3;[4-(3-oxocyclobutyl)phenyl]boronic Acid;3-(4-Boronophenyl)cyclobutanone;4-(3-oxocyclobutyl)phenylboronic acid;(4-(3-Oxocyclobutyl)phenyl)boronicacid;DTXSID20400705;AKOS016004374;AB15459;3-(4-dihydroxyborylphenyl)cyclobutanone;CS-0174210;FT-0763347;EN300-761685;F53558

Suppliers and Price of (4-(3-Oxocyclobutyl)phenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(4-(3-Oxocyclobutyl)phenyl)boronic acid 95+%
1g
$ 1647.00

Matrix Scientific
(4-(3-Oxocyclobutyl)phenyl)boronic acid 95+%
250mg
$ 742.00

Crysdot
(4-(3-Oxocyclobutyl)phenyl)boronicacid 95+%
1g
$ 772.00

Chemenu
(4-(3-Oxocyclobutyl)phenyl)boronicacid 95+%
1g
$ 634.00

Alichem
(4-(3-Oxocyclobutyl)phenyl)boronicacid
1g
$ 615.44

AK Scientific
(4-(3-Oxocyclobutyl)phenyl)boronicacid
1g
$ 2273.00

AK Scientific
(4-(3-Oxocyclobutyl)phenyl)boronicacid
250mg
$ 1051.00

Total 15 raw suppliers

Chemical Property of (4-(3-Oxocyclobutyl)phenyl)boronic acid

Chemical Property:

Vapor Pressure:4.93E-07mmHg at 25°C
Melting Point:94-98 °C
Refractive Index:1.572
Boiling Point:397.5 °C at 760 mmHg
PKA:8.62±0.17(Predicted)
Flash Point:194.2 °C
PSA：57.53000
Density:1.25 g/cm³
LogP:-0.18710
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:190.0801244
Heavy Atom Count:14
Complexity:213

Purity/Quality:

98%min ^*data from raw suppliers

(4-(3-Oxocyclobutyl)phenyl)boronic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC=C(C=C1)C2CC(=O)C2)(O)O

Technology Process of (4-(3-Oxocyclobutyl)phenyl)boronic acid

There total 5 articles about (4-(3-Oxocyclobutyl)phenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 254892-99-4
3-(4-boronophenyl)cyclobutanone ethylene ketal

: 254893-03-3
3-(4-boronophenyl)cyclobutanone

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃;
DOI:10.1021/jo990878c

Reference yield:

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 254893-03-3
3-(4-boronophenyl)cyclobutanone

Guidance literature:: Multi-step reaction with 5 steps

1.1: Zn-Cu; POCl₃ / diethyl ether / 4 h / 20 °C / Heating

2.1: Zn; AcOH / 2.5 h / 20 - 120 °C

3.1: 82.5 percent / p-TsOH / benzene / 20 h / 120 °C

4.1: BuLi / hexane; tetrahydrofuran / 0.5 h / -70 °C

4.2: B(OiPr)3 / tetrahydrofuran; hexane / -70 - 20 °C

4.3: 83 percent / H₂SO₄ / H₂O / 0.5 h / 0 °C

5.1: 79 percent / HCl / methanol / 20 °C

With hydrogenchloride; n-butyllithium; copper; toluene-4-sulfonic acid; acetic acid; zinc; trichlorophosphate; In tetrahydrofuran; methanol; diethyl ether; hexane; benzene; 1.1: Cycloaddition / 2.1: Dehalogenation / 3.1: Cyclization / 4.1: Metallation / 4.2: Substitution / 4.3: Hydrolysis / 5.1: Ring cleavage;
DOI:10.1021/jo990878c

Reference yield:

: 254892-91-6
3-(4-bromophenyl)cyclobutanone

: 254893-03-3
3-(4-boronophenyl)cyclobutanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 82.5 percent / p-TsOH / benzene / 20 h / 120 °C

2.1: BuLi / hexane; tetrahydrofuran / 0.5 h / -70 °C

2.2: B(OiPr)3 / tetrahydrofuran; hexane / -70 - 20 °C

2.3: 83 percent / H₂SO₄ / H₂O / 0.5 h / 0 °C

3.1: 79 percent / HCl / methanol / 20 °C

With hydrogenchloride; n-butyllithium; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; hexane; benzene; 1.1: Cyclization / 2.1: Metallation / 2.2: Substitution / 2.3: Hydrolysis / 3.1: Ring cleavage;
DOI:10.1021/jo990878c