N'-(diphenylmethylene)formohydrazide

Base Information

• Chemical Name: N'-(diphenylmethylene)formohydrazide
• CAS No.: 408531-60-2
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.262
• Mol file: 408531-60-2.mol

Synonyms:N'-(diphenylmethylene)formohydrazide

Chemical Property of N'-(diphenylmethylene)formohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-(diphenylmethylene)formohydrazide

There total 2 articles about N'-(diphenylmethylene)formohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

carbon dioxide (124-38-9,18923-20-1) + benzophenone hydrazone (5350-57-2) → N'-(diphenylmethylene)formohydrazide (408531-60-2)

Guidance literature:

With phenylsilane; caesium carbonate; In acetonitrile; at 20 ℃; for 12h; under 750.075 Torr;

DOI:10.1021/acscatal.6b01856

Reference yield: 40.0%

→ N'-(diphenylmethylene)formohydrazide (408531-60-2)

Guidance literature:

With C₂₁H₂₄N₂; phenylsilane; In tetrahydrofuran; at 20 ℃; for 24h; under 750.075 - 2250.23 Torr; Inert atmosphere; Glovebox;

Reference yield:

2-chloro-5-(chloromethyl)pyridine (70258-18-3) + N'-(diphenylmethylene)formohydrazide (408531-60-2) → C20H16ClN3O

Guidance literature:

N'-(diphenylmethylene)formohydrazide; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h;

2-chloro-5-(chloromethyl)pyridine; In N,N-dimethyl-formamide; at 80 ℃; for 3h;

DOI:10.1002/ejoc.201900637

upstream raw materials:

carbon dioxide

benzophenone hydrazone