Technology Process of C22H25NO
There total 7 articles about C22H25NO which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanesulfonic acid; phosphorus pentoxide;
at 110 - 120 ℃;
for 1.5h;
DOI:10.1021/jm00029a008
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 90 percent / NaOH / tetrahydrofuran / 22 h / Heating
2: 1.) lithium diisopropylamide / 1.) THF, hexane, -70 deg C, 1 h, 2.) THF, hexane, RT, 22 h
3: TFA / 17 h / Heating
4: Et3N / tetrahydrofuran / 22 h / Heating
5: aq. NaOH / ethanol / 17 h / Heating
6: P2O5, methanesulfonic acid / 1.5 h / 110 - 120 °C
With
sodium hydroxide; methanesulfonic acid; phosphorus pentoxide; triethylamine; trifluoroacetic acid; lithium diisopropyl amide;
In
tetrahydrofuran; ethanol;
DOI:10.1021/jm00029a008
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Et3N / tetrahydrofuran / 22 h / Heating
2: aq. NaOH / ethanol / 17 h / Heating
3: P2O5, methanesulfonic acid / 1.5 h / 110 - 120 °C
With
sodium hydroxide; methanesulfonic acid; phosphorus pentoxide; triethylamine;
In
tetrahydrofuran; ethanol;
DOI:10.1021/jm00029a008