5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

Base Information

Chemical Name:5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine
CAS No.:828261-38-7
Molecular Formula:C₃₇H₃₆N₄O₇
Molecular Weight:648.715
Hs Code.:

5'-O-<bis(4-methoxyphenyl)(phenyl)methyl>-2'deoxy-N<sup>4</sup>-phenylcarbamoylcytidine

Synonyms:5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

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Technology Process of 5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

There total 6 articles about 5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 219582-35-1
2'-deoxy-N⁴-[(phenylamino)carbonyl]cytidine

: 828261-38-7
5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

Guidance literature:: In pyridine; at 20 ℃; for 4h;
DOI:10.1016/j.tetlet.2004.10.116

Reference yield:

: 103-71-9
phenyl isocyanate

: 828261-38-7
5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / triethylamine / dimethylformamide / 0.5 h / 20 °C

2: 87 percent / pyridine / 4 h / 20 °C

With triethylamine; In pyridine; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2004.10.116

Reference yield:

: 951-77-9
2'-Deoxycytidine

: 828261-38-7
5'-O--2'deoxy-N⁴-phenylcarbamoylcytidine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / triethylamine / dimethylformamide / 0.5 h / 20 °C

2: 87 percent / pyridine / 4 h / 20 °C

With triethylamine; In pyridine; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2004.10.116