1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

Base Information

Chemical Name:1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene
CAS No.:180200-86-6
Molecular Formula:C8H8 Br Cl O2 S
Molecular Weight:283.573
Hs Code.:2935009090
European Community (EC) Number:674-403-0
DSSTox Substance ID:DTXSID90375532
Wikidata:Q82164097
Mol file:180200-86-6.mol

Synonyms:1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene;180200-86-6;1-(bromomethyl)-2-chloro-4-methylsulfonylbenzene;2-chloro-4-(methylsulphonyl)benzyl bromide;1-(bromomethyl)-2-chloro-4-(methylsulfonyl)-benzene;Benzene,1-(bromomethyl)-2-chloro-4-(methylsulfonyl)-;1-(bromomethyl)-2-chloro-4-methanesulfonylbenzene;SCHEMBL399056;Benzene, 1-(bromomethyl)-2-chloro-4-(methylsulfonyl)-;DTXSID90375532;FQVJALWTFNYNBL-UHFFFAOYSA-N;MFCD04037959;AKOS015836014;PS-9936;2-chloro-4-methylsulfonylbenzyl bromide;FT-0676500;1-bromomethyl-2-chloro-4-methanesulfonylbenzene;1-Bromomethyl-2-chloro-4-methanesulfonyl-benzene;1-bromomethyl-2-chloro-4-(methylsulfonyl)benzene;A812532;J-011512

Suppliers and Price of 1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene
25mg
$ 45.00

TRC
1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene
250mg
$ 75.00

SynQuest Laboratories
2-Chloro-4-(methylsulfonyl)benzyl bromide
5 g
$ 404.00

SynQuest Laboratories
2-Chloro-4-(methylsulfonyl)benzyl bromide
250 mg
$ 61.00

SynQuest Laboratories
2-Chloro-4-(methylsulfonyl)benzyl bromide
1 g
$ 141.00

Oakwood
4-Chloro-N-cyclopropyl-N-piperidin-4-ylbenzenesulfonamide
250mg
$ 86.00

Matrix Scientific
1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)-benzene
1g
$ 130.00

Matrix Scientific
1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)-benzene
5g
$ 388.00

Labseeker
1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene 95
5g
$ 1333.00

Apolloscientific
2-Chloro-4-(methylsulphonyl)benzylbromide 95+%
100mg
$ 15.00

Total 11 raw suppliers

Chemical Property of 1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

Chemical Property:

Vapor Pressure:1.61E-06mmHg at 25°C
Melting Point:103-105
Boiling Point:408.8°Cat760mmHg
Flash Point:201°C
PSA：42.52000
Density:1.642g/cm³
LogP:3.71920
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:281.91169
Heavy Atom Count:13
Complexity:260

Purity/Quality:

97% ^*data from raw suppliers

1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC(=C(C=C1)CBr)Cl

Technology Process of 1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

There total 3 articles about 1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 181300-40-3
[2-chloro-4-(methylsulfonyl)phenyl]methanol

: 180200-86-6
1-(bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

Guidance literature:: With phosphorus tribromide; In diethyl ether; at 20 ℃; for 4h;

Reference yield:

: 84194-36-5
2-chloro-4-fluorobenzaldehyde

: 180200-86-6
1-(bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1: dimethyl sulfoxide / 16 h / 90 °C

2: sodium tetrahydroborate / ethanol / 0 - 20 °C

3: phosphorus tribromide / diethyl ether / 16 h / 0 - 20 °C

With sodium tetrahydroborate; phosphorus tribromide; In diethyl ether; ethanol; dimethyl sulfoxide;
DOI:10.1021/acsmedchemlett.7b00157

Reference yield:

: 101349-95-5
2-chloro-4-(methylsulfonyl)benzaldehyde

: 180200-86-6
1-(bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 0 - 20 °C

2: phosphorus tribromide / diethyl ether / 16 h / 0 - 20 °C

With sodium tetrahydroborate; phosphorus tribromide; In diethyl ether; ethanol;
DOI:10.1021/acsmedchemlett.7b00157