2-(Pyrrolidin-1-yl)aniline

Base Information

Chemical Name:2-(Pyrrolidin-1-yl)aniline
CAS No.:21627-58-7
Molecular Formula:C10H14N2
Molecular Weight:162.235
Hs Code.:2933990090
European Community (EC) Number:858-540-5
DSSTox Substance ID:DTXSID60359086
Nikkaji Number:J2.714.977D
Wikidata:Q82140100
ChEMBL ID:CHEMBL4085391
Mol file:21627-58-7.mol

Synonyms:2-(pyrrolidin-1-yl)aniline;21627-58-7;2-pyrrolidin-1-ylaniline;2-Pyrrolidinoaniline;2-Pyrrolidin-1-yl-phenylamine;(2-pyrrolidin-1-ylphenyl)amine;2-(1-pyrrolidinyl)-benzenamine;1458593-63-9;Oprea1_739218;2-pyrrolidin-1-ylphenylamine;1-(2-aminophenyl)pyrrolidine;SCHEMBL484010;CHEMBL4085391;AMY4681;DTXSID60359086;Benzenamine,2-(1-pyrrolidinyl)-;BFPUBGCFJMIZDF-UHFFFAOYSA-N;HMS1704G19;2-(1-PYRROLIDINYL)ANILINE;WAA62758;1-(2-aminophenyl)-tetrahydropyrrole;BBL030016;MFCD03563756;STK347454;AKOS000103040;AB93279;(2-Pyrrolidin-1-ylphenyl)amine, AldrichCPR;BB 0245665;CS-0206021;FT-0638136;EN300-35304;C78056;F8881-3132

Suppliers and Price of 2-(Pyrrolidin-1-yl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Pyrrolidin-1-yl)aniline
2.5g
$ 310.00

SynQuest Laboratories
2-Pyrrolidin-1-ylaniline 97%
250 mg
$ 64.00

SynQuest Laboratories
2-Pyrrolidin-1-ylaniline 97%
1 g
$ 104.00

SynQuest Laboratories
2-Pyrrolidin-1-ylaniline 97%
5 g
$ 280.00

Sigma-Aldrich
(2-Pyrrolidin-1-ylphenyl)amine Aldrich
1g
$ 129.00

Crysdot
2-(Pyrrolidin-1-yl)aniline 95+%
10g
$ 393.00

Crysdot
2-(Pyrrolidin-1-yl)aniline 95+%
25g
$ 752.00

CHESS?
AN009753:2-Pyrrolidin-1-yl-phenylamine 96
1 g
$ 174.00

CHESS?
AN009753:2-Pyrrolidin-1-yl-phenylamine 96
5 g
$ 474.00

Chemenu
2-Pyrrolidin-1-yl-phenylamine 95%
10g
$ 371.00

Total 15 raw suppliers

Chemical Property of 2-(Pyrrolidin-1-yl)aniline

Chemical Property:

Vapor Pressure:0.00145mmHg at 25°C
Refractive Index:1.609
Boiling Point:296.2 °C at 760 mmHg
Flash Point:115.6 °C
PSA：29.26000
Density:1.109 g/cm³
LogP:2.51520
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.115698455
Heavy Atom Count:12
Complexity:141

Purity/Quality:

99% ^*data from raw suppliers

2-(Pyrrolidin-1-yl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=CC=CC=C2N

Technology Process of 2-(Pyrrolidin-1-yl)aniline

There total 7 articles about 2-(Pyrrolidin-1-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 40832-79-9
1-(2-nitrophenyl)pyrrolidine

: 21627-58-7
2-(pyrrolidin-1-yl)-phenylamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 20h;

Reference yield: 35.0%

: 7724-48-3
2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazole

: 21627-58-7
2-(pyrrolidin-1-yl)-phenylamine

: 39161-58-5
1,2,3,4,5,6-hexahydro-benzo[b][1,4]diazocine

Guidance literature:: 2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazole; With diisobutylaluminium hydride; In toluene; at 0 ℃; for 23h; Inert atmosphere; Reflux;

With water; sodium fluoride; In toluene; benzene; at 0 - 20 ℃; for 0.333333h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2013.11.025

Reference yield:

: 1493-27-2,127723-77-7
ortho-nitrofluorobenzene

: 21627-58-7
2-(pyrrolidin-1-yl)-phenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1 h / 20 °C

2: palladium on activated charcoal; hydrogen / methanol / 4 h / 775.74 Torr

With palladium on activated charcoal; hydrogen; In methanol;