(R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

Base Information

Chemical Name:(R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide
CAS No.:249743-98-4
Molecular Formula:C₁₆H₂₃BrOS
Molecular Weight:343.328
Hs Code.:

Synonyms:(R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

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Chemical Property of (R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

Chemical Property:

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Technology Process of (R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

There total 5 articles about (R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 249743-99-5
(R)-trans-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

: 249743-98-4
(R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

Guidance literature:: (R)-trans-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide; With lithium diisopropyl amide; In tetrahydrofuran; at -30 ℃;

With water; In tetrahydrofuran; Further stages.;
DOI:10.1021/ol990859p

Reference yield:

: menthyl (S)-2-bromophenylsulfinate

: 16133-41-8
cis-1-(tert-butyl)-4-iodocyclohexane

: 249743-99-5
(R)-trans-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

: 249743-98-4
(R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

Guidance literature:: cis-1-(tert-butyl)-4-iodocyclohexane; With magnesium; In diethyl ether;

menthyl (S)-2-bromophenylsulfinate; In diethyl ether; benzene; at 0 - 20 ℃; Further stages.;
DOI:10.1021/ol990859p

Reference yield:

: 98-52-2
4-(1,1-dimethylethyl)-cyclohexanol

: 249743-98-4
(R)-cis-2-bromophenyl 4-(tert-butyl)cyclohexyl sulfoxide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 29 percent / iodine; imidazole; PPh₃ / toluene / 4 h / 60 °C

2.1: Mg / diethyl ether

2.2: diethyl ether; benzene / 0 - 20 °C

3.1: lithium diisopropylamide / tetrahydrofuran / -30 °C

3.2: water / tetrahydrofuran

With 1H-imidazole; iodine; magnesium; triphenylphosphine; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; toluene;
DOI:10.1021/ol990859p