2-(5-Ethynylthiophen-2-yl)pyridine

Base Information

Chemical Name:2-(5-Ethynylthiophen-2-yl)pyridine
CAS No.:132464-90-5
Molecular Formula:C11H7 N S
Molecular Weight:185.24
Hs Code.:2933399990
European Community (EC) Number:641-201-9
DSSTox Substance ID:DTXSID70567973
Wikidata:Q82454053
Mol file:132464-90-5.mol

Synonyms:132464-90-5;2-(5-Ethynylthien-2-yl)pyridine;2-(5-ethynylthiophen-2-yl)pyridine;Pyridine,2-(5-ethynyl-2-thienyl)-;SCHEMBL18297699;DTXSID70567973;AKOS006237430;PS-11552;CS-0315193;W-205406;F2167-5115

Suppliers and Price of 2-(5-Ethynylthiophen-2-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(5-Ethynylthien-2-yl)pyridine
100mg
$ 220.00

TRC
2-(5-Ethynylthien-2-yl)pyridine
50mg
$ 155.00

SynQuest Laboratories
2-(5-Ethynylthien-2-yl)pyridine 97%
250 mg
$ 228.00

SynQuest Laboratories
2-(5-Ethynylthien-2-yl)pyridine 97%
50 mg
$ 64.00

SynQuest Laboratories
2-(5-Ethynylthien-2-yl)pyridine 97%
1 g
$ 532.00

Crysdot
2-(5-Ethynylthiophen-2-yl)pyridine 95+%
1g
$ 933.00

Apolloscientific
2-(5-Ethynylthien-2-yl)pyridine 97%
250mg
$ 206.00

Apolloscientific
2-(5-Ethynylthien-2-yl)pyridine 97%
50mg
$ 58.00

Apolloscientific
2-(5-Ethynylthien-2-yl)pyridine 97%
1g
$ 482.00

American Custom Chemicals Corporation
2-(5-ETHYNYLTHIEN-2-YL)PYRIDINE 95.00%
1G
$ 1060.66

Total 9 raw suppliers

Chemical Property of 2-(5-Ethynylthiophen-2-yl)pyridine

Chemical Property:

Vapor Pressure:0.000563mmHg at 25°C
Melting Point:109 °C
Boiling Point:321.3°Cat760mmHg
PKA:3.40±0.19(Predicted)
Flash Point:145°C
PSA：41.13000
Density:1.22g/cm³
LogP:2.79140
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:185.02992040
Heavy Atom Count:13
Complexity:217

Purity/Quality:

98%min ^*data from raw suppliers

2-(5-Ethynylthien-2-yl)pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=CC=C(S1)C2=CC=CC=N2

Technology Process of 2-(5-Ethynylthiophen-2-yl)pyridine

There total 3 articles about 2-(5-Ethynylthiophen-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 868755-72-0
2-(5-Trimethylsilanylethynyl-thiophen-2-yl)-pyridine

: 132464-90-5
2-(5-ethynylthiophen-2-yl)pyridine

Guidance literature:: With potassium carbonate; In methanol; for 2h; Yield given; Ambient temperature;
DOI:10.1021/jm00108a031

Reference yield:

: 123784-07-6
2-(5-bromothiophen-2-yl)pyridine

: 132464-90-5
2-(5-ethynylthiophen-2-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P, CuI, Et₃N, palladium acetate / acetonitrile / 2 h / Ambient temperature

2: K₂CO₃ / methanol / 2 h / Ambient temperature

With copper(l) iodide; palladium diacetate; potassium carbonate; triethylamine; triphenylphosphine; In methanol; acetonitrile;
DOI:10.1021/jm00108a031

Reference yield:

: 3319-99-1
2'-(2-thienyl)pyridine

: 132464-90-5
2-(5-ethynylthiophen-2-yl)pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 9.5 g / Br₂ / CH₂Cl₂ / 0.17 h

2: Ph₃P, CuI, Et₃N, palladium acetate / acetonitrile / 2 h / Ambient temperature

3: K₂CO₃ / methanol / 2 h / Ambient temperature

With copper(l) iodide; bromine; palladium diacetate; potassium carbonate; triethylamine; triphenylphosphine; In methanol; dichloromethane; acetonitrile;
DOI:10.1021/jm00108a031