spirotryprostatin A

Base Information

• Chemical Name: spirotryprostatin A
• CAS No.: 182234-25-9
• Molecular Formula: C₂₂H₂₅N₃O₄
• Molecular Weight: 395.458
• DSSTox Substance ID: DTXSID501046361
• Nikkaji Number: J1.098.992B
• Wikipedia: Spirotryprostatin_A
• Wikidata: Q7578222
• Metabolomics Workbench ID: 119027
• ChEMBL ID: CHEMBL549475

Synonyms:spirotryprostatin A

Chemical Property of spirotryprostatin A

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 395.18450629
• Heavy Atom Count: 29
• Complexity: 791

Purity/Quality:

98.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=CC1C2(CC3N1C(=O)C4CCCN4C3=O)C5=C(C=C(C=C5)OC)NC2=O)C
• Isomeric SMILES: CC(=C[C@H]1[C@]2(C[C@@H]3N1C(=O)[C@@H]4CCCN4C3=O)C5=C(C=C(C=C5)OC)NC2=O)C

Technology Process of spirotryprostatin A

There total 43 articles about spirotryprostatin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-Methoxyspirotryprostatin B (1031727-28-2) → Spirotryprostatin A (182234-25-9)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 2h; under 760.051 Torr;

DOI:10.1002/chem.201806411

Reference yield: 43.0%

(2S,3S,5aS,10aS)-1',2',5a,6,7,8,10,10a-octahydro-6'-methoxy-3-(2-methoxy-2-methylpropyl)-2',5,10-trioxospiro[1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole] (599185-52-1) → Spirotryprostatin A (182234-25-9) + (2S,3S,5aS,10aS)-1',2',5a,6,7,8,10,10a-octahydro-6'-methoxy-3-(2-hydroxy-2-methylpropyl)-2',5,10-trioxospiro[1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]

Guidance literature:

With water; toluene-4-sulfonic acid; In toluene; at 110 ℃;

DOI:10.1021/ol0351910

Reference yield: 41.0%

C22H25N3O4 (208761-41-5) → Spirotryprostatin A (182234-25-9)

Guidance literature:

With rhodium(III) chloride; In ethanol; Heating;

DOI:10.1002/(SICI)1521-3773(19980504)37:8<1138::AID-ANIE1138>3.0.CO;2-N

upstream raw materials:

C₂₂H₂₅N₃O₄

(2S,3S,5aS,10aS)-1',2',5a,6,7,8,10,10a-octahydro-6'-methoxy-3-(2-methoxy-2-methylpropyl)-2',5,10-trioxospiro[1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]

methanol

6-bromodemethoxyspirotryprostatin A

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 182234-25-9 Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione,1,5a,6,7,8,10a-hexahydro-6'-methoxy-3-(2-methyl-1-propen-1-yl)-,(2S,3S,5aS,10aS)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send