N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Base Information

Chemical Name:N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide
CAS No.:690273-46-2
Molecular Formula:C₂₄H₂₄F₃N₃OS
Molecular Weight:459.535
Hs Code.:

Synonyms:N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Suppliers and Price of N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

There total 4 articles about N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 120115-93-7
1-benzyl-4-(4-methylthiazol-2-yl)-4-anilinopiperidine

: 76-05-1
trifluoroacetic acid

: 690273-46-2
N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Guidance literature:: With triethylamine; dmap; In dichloromethane; at 0 - 20 ℃; for 2.25h;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 690273-46-2
N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / 1.17 h / 0 - 40 °C

1.2: 0 °C / pH 10

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C

2.2: 0.5 h / -30 - 0 °C

3.1: triethylamine / dmap / dichloromethane / 2.25 h / 0 - 20 °C

With n-butyllithium; triethylamine; dmap; In tetrahydrofuran; hexane; dichloromethane; acetic acid;

Reference yield:

: 968-86-5
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile

: 690273-46-2
N-[1-benzyl-4-(4-methylthiazol-2-yl)-4-piperidinyl]-2,2,2-trifluoro-N-phenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C

1.2: 0.5 h / -30 - 0 °C

2.1: triethylamine / dmap / dichloromethane / 2.25 h / 0 - 20 °C

With n-butyllithium; triethylamine; dmap; In tetrahydrofuran; hexane; dichloromethane;