Amthamine dihydrobromide

Base Information

• Chemical Name: Amthamine dihydrobromide
• CAS No.: 142457-00-9
• Molecular Formula: 2BrH*C₆H₁₁N₃S
• Molecular Weight: 319.063
• DSSTox Substance ID: DTXSID20585061
• Mol file: 142457-00-9.mol

Synonyms:2-amino-5-(2-aminoethyl)-4-methylthiazole;amthamine;amthamine dihydrobromide

Chemical Property of Amthamine dihydrobromide

Chemical Property:

• Vapor Pressure: 1.89E-06mmHg at 25°C
• Boiling Point: 386.3°C at 760 mmHg
• Flash Point: 187.4°C
• PSA: 93.90000
• LogP: 3.08150
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble27mg/mL
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 318.91764
• Heavy Atom Count: 12
• Complexity: 109

Purity/Quality:

99%, ^*data from raw suppliers

Amthamine dihydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(SC(=N1)N)CCN.Br.Br

Technology Process of Amthamine dihydrobromide

There total 4 articles about Amthamine dihydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.2%

2-amino-4-methyl-5-(2-phtalimidoethyl)thiazole hydrobromide (136604-53-0) → Amthamine dihydrobromide (142457-00-9)

Guidance literature:

With hydrogen bromide; for 5h; Heating;

DOI:10.1021/jm00095a021

Reference yield:

5-chloro-2-pentanone (5891-21-4) → Amthamine dihydrobromide (142457-00-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 62.8 percent / K₂CO₃, KI / dimethylformamide / 3 h / 110 °C

2: 63.5 percent / Br₂ / CCl₄ / 3 h / Ambient temperature

3: 55.3 percent / dimethylformamide / 3 h / 120 °C

4: 75.2 percent / 30percent aq. HBr / 5 h / Heating

With hydrogen bromide; bromine; potassium carbonate; potassium iodide; In tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00095a021

Reference yield:

2-(4-oxopentyl)isoindole-1,3-dione (3197-25-9) → Amthamine dihydrobromide (142457-00-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 63.5 percent / Br₂ / CCl₄ / 3 h / Ambient temperature

2: 55.3 percent / dimethylformamide / 3 h / 120 °C

3: 75.2 percent / 30percent aq. HBr / 5 h / Heating

With hydrogen bromide; bromine; In tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00095a021

upstream raw materials:

2-amino-4-methyl-5-(2-phtalimidoethyl)thiazole hydrobromide

5-chloro-2-pentanone

2-(4-oxopentyl)isoindole-1,3-dione

3-bromo-5-phtalimido-2-pentanone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 142457-00-9 AMTHAMINE DIHYDROBROMIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send