Technology Process of benzyl 4-amino-1H-pyrrolo[3,2-c]pyridine-1-carboxylate
There total 8 articles about benzyl 4-amino-1H-pyrrolo[3,2-c]pyridine-1-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
benzyl 4-[(2,4,4-trimethylpentan-2-yl)amino]-1H-pyrrolo[3,2-c]pyridine-1-carboxylate;
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
Cooling with ice;
With
ammonia;
In
water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogen / palladium 10% on activated carbon / methanol / 2 h
2.1: triethylamine / dichloromethane / 1 h / 0 - 20 °C
3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane; Dimethyl ether / 4 h / 20 °C
4.1: chloroform / 0.25 h
4.2: 1 h / 0 - 20 °C
5.1: trifluoroacetic acid / dichloromethane / 20 °C / Cooling with ice
With
hydrogen; triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid;
palladium 10% on activated carbon;
In
methanol; Dimethyl ether; dichloromethane; chloroform;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: nitric acid / sulfuric acid / 2 h / 0 - 100 °C
2.1: dimethyl amine / N,N-dimethyl-formamide / 15 h / 90 °C
3.1: hydrogen / palladium 10% on activated carbon / methanol / 2 h
4.1: triethylamine / dichloromethane / 1 h / 0 - 20 °C
5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane; Dimethyl ether / 4 h / 20 °C
6.1: chloroform / 0.25 h
6.2: 1 h / 0 - 20 °C
7.1: trifluoroacetic acid / dichloromethane / 20 °C / Cooling with ice
With
hydrogen; nitric acid; dimethyl amine; triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid;
sulfuric acid; palladium 10% on activated carbon;
In
methanol; Dimethyl ether; dichloromethane; chloroform; N,N-dimethyl-formamide;