Technology Process of 5-(n-decyloxy)-2-fluorophenol
There total 8 articles about 5-(n-decyloxy)-2-fluorophenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
ethanol;
at 0 - 80 ℃;
DOI:10.1021/ol200808q
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetra-(n-butyl)ammonium iodide; potassium carbonate / acetone / 20 h / Reflux
2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / 760.05 Torr / Inert atmosphere
3: [bis(acetoxy)iodo]benzene; magnesium oxide / chloroform / 0 - 20 °C
4: (bis-(2-methoxyethyl)amino)sulfur trufluoride / chloroform / 0 - 20 °C / Inert atmosphere
5: sodium tetrahydroborate; 1,8-diazabicyclo[5.4.0]undec-7-ene / ethanol / 0 - 80 °C
With
sodium tetrahydroborate; [bis(acetoxy)iodo]benzene; palladium 10% on activated carbon; hydrogen; magnesium oxide; tetra-(n-butyl)ammonium iodide; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; (bis-(2-methoxyethyl)amino)sulfur trufluoride;
In
methanol; ethanol; chloroform; acetone;
DOI:10.1021/ol200808q
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (bis-(2-methoxyethyl)amino)sulfur trufluoride / chloroform / 0 - 20 °C / Inert atmosphere
2: sodium tetrahydroborate; 1,8-diazabicyclo[5.4.0]undec-7-ene / ethanol / 0 - 80 °C
With
sodium tetrahydroborate; 1,8-diazabicyclo[5.4.0]undec-7-ene; (bis-(2-methoxyethyl)amino)sulfur trufluoride;
In
ethanol; chloroform;
DOI:10.1021/ol200808q
