Technology Process of 3-(n-decyloxy)-6,6-difluorocyclohexa-2,4-dienone
There total 7 articles about 3-(n-decyloxy)-6,6-difluorocyclohexa-2,4-dienone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(bis-(2-methoxyethyl)amino)sulfur trufluoride;
In
chloroform;
at 0 - 20 ℃;
chemoselective reaction;
Inert atmosphere;
DOI:10.1021/ol200808q
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetra-(n-butyl)ammonium iodide; potassium carbonate / acetone / 20 h / Reflux
2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / 760.05 Torr / Inert atmosphere
3: [bis(acetoxy)iodo]benzene; magnesium oxide / chloroform / 0 - 20 °C
4: (bis-(2-methoxyethyl)amino)sulfur trufluoride / chloroform / 0 - 20 °C / Inert atmosphere
With
[bis(acetoxy)iodo]benzene; palladium 10% on activated carbon; hydrogen; magnesium oxide; tetra-(n-butyl)ammonium iodide; potassium carbonate; (bis-(2-methoxyethyl)amino)sulfur trufluoride;
In
methanol; chloroform; acetone;
DOI:10.1021/ol200808q
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C
2: potassium carbonate / methanol / 1 h / 20 °C
3: tetra-(n-butyl)ammonium iodide; potassium carbonate / acetone / 20 h / Reflux
4: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / 760.05 Torr / Inert atmosphere
5: [bis(acetoxy)iodo]benzene; magnesium oxide / chloroform / 0 - 20 °C
6: (bis-(2-methoxyethyl)amino)sulfur trufluoride / chloroform / 0 - 20 °C / Inert atmosphere
With
[bis(acetoxy)iodo]benzene; palladium 10% on activated carbon; hydrogen; magnesium oxide; tetra-(n-butyl)ammonium iodide; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; (bis-(2-methoxyethyl)amino)sulfur trufluoride;
In
methanol; dichloromethane; chloroform; acetone;
DOI:10.1021/ol200808q
