6-Methyl-4-nitropyridine-2-carbonitrile

Base Information

Chemical Name:6-Methyl-4-nitropyridine-2-carbonitrile
CAS No.:30235-12-2
Molecular Formula:C7H5N3O2
Molecular Weight:163.136
Hs Code.:2933399090
European Community (EC) Number:625-211-0
DSSTox Substance ID:DTXSID80464005
Nikkaji Number:J1.754.406C
Wikidata:Q82289164
Mol file:30235-12-2.mol

Synonyms:30235-12-2;6-methyl-4-nitropicolinonitrile;6-Methyl-4-nitropyridine-2-carbonitrile;2-CYANO-6-METHYL-4-NITROPYRIDINE;2-Pyridinecarbonitrile, 6-methyl-4-nitro-;SCHEMBL1798954;DTXSID80464005;VITXYPUCOQUWPJ-UHFFFAOYSA-N;MFCD09839154;AKOS015891875;SB53840;AS-80810;CS-0105781;FT-0726611;6-Methyl-4-nitropyridine-2-carbonitrile, 97%;J-017839

Suppliers and Price of 6-Methyl-4-nitropyridine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methyl-4-nitropyridine-2-carbonitrile
100mg
$ 45.00

Sigma-Aldrich
6-Methyl-4-nitropyridine-2-carbonitrile 97%
5g
$ 232.00

Sigma-Aldrich
6-Methyl-4-nitropyridine-2-carbonitrile 97%
1g
$ 67.00

Crysdot
6-Methyl-4-nitropicolinonitrile 95+%
25g
$ 566.00

Chemenu
6-methyl-4-nitropicolinonitrile 95%
25g
$ 535.00

American Custom Chemicals Corporation
6-METHYL-4-NITROPYRIDINE-2-CARBONITRILE 95.00%
5G
$ 992.64

American Custom Chemicals Corporation
6-METHYL-4-NITROPYRIDINE-2-CARBONITRILE 95.00%
1G
$ 667.50

Alichem
6-Methyl-4-nitropicolinonitrile
1g
$ 2779.20

Alichem
6-Methyl-4-nitropicolinonitrile
500mg
$ 1836.65

Total 22 raw suppliers

Chemical Property of 6-Methyl-4-nitropyridine-2-carbonitrile

Chemical Property:

Vapor Pressure:0.000368mmHg at 25°C
Melting Point:74-79oC
Refractive Index:1.57
Boiling Point:318.2 °C at 760 mmHg
Flash Point:146.2 °C
PSA：82.50000
Density:1.34 g/cm³
LogP:1.69308
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:163.038176411
Heavy Atom Count:12
Complexity:227

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-4-nitropyridine-2-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25-37/38-41
Safety Statements: 26-39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=N1)C#N)[N+](=O)[O-]
Uses 6-Methyl-4-nitropyridine-2-carbonitrile is used in the synthesis of hydrochloride of 2-methyl-4-pyrrolidinyl-6-[(E)-2-(3-trifluoromethylphenyl)vinyl]pyridine, a selective Y5 receptor antagonist.

Technology Process of 6-Methyl-4-nitropyridine-2-carbonitrile

There total 3 articles about 6-Methyl-4-nitropyridine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 773837-37-9
sodium cyanide

: 5470-66-6
2-methyl-4-nitropyridine N-oxide

: 30235-12-2
6-methyl-4-nitropyridine-2-carbonitrile

Guidance literature:: 2-methyl-4-nitropyridine N-oxide; With dimethyl sulfate; at 65 - 70 ℃; for 2h;

sodium cyanide; In water; at -10 ℃; for 3.6h; Inert atmosphere;

Reference yield: 72.0%

: 5470-66-6
2-methyl-4-nitropyridine N-oxide

: 30235-12-2
6-methyl-4-nitropyridine-2-carbonitrile

Guidance literature:: With dimethyl sulfate; In hexane; water; ethyl acetate;

Reference yield: 50.0%

: 5470-66-6
2-methyl-4-nitropyridine N-oxide

: 151-50-8
potassium cyanide

: 30235-12-2
6-methyl-4-nitropyridine-2-carbonitrile

Guidance literature:: 2-methyl-4-nitropyridine N-oxide; With dimethyl sulfate; at 70 ℃; for 1h;

potassium cyanide; In water; at 0 - 20 ℃;
DOI:10.1081/SCC-120004266