3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid

Base Information

• Chemical Name: 3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid
• CAS No.: 1166841-61-7
• Molecular Formula: C₃₃H₃₂N₆O₃
• Molecular Weight: 560.655
• Mol file: 1166841-61-7.mol

Synonyms:3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid

Chemical Property of 3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid

There total 2 articles about 3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.3%

methyl 3,5-bis[bis(pyridin-2-ylmethyl)aminomethyl]-4-hydroxybenzoate (1049723-58-1) → 3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid (1166841-61-7)

Guidance literature:

With sodium hydroxide; In ethanol; Reflux;

DOI:10.1016/j.tet.2009.03.051

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + bis[(2-pyridyl)methyl]amine (1539-42-0) → 3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxybenzoic acid (1166841-61-7)

Guidance literature:

formaldehyd; bis[(2-pyridyl)methyl]amine; paraben; With hydrogenchloride; In ethanol; water; for 72h; Reflux;

With water; sodium hydroxide; In ethanol; at 60 ℃; for 48h;

upstream raw materials:

methyl 3,5-bis[bis(pyridin-2-ylmethyl)aminomethyl]-4-hydroxybenzoate

formaldehyd

bis[(2-pyridyl)methyl]amine