(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

Base Information

Chemical Name:(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide
CAS No.:1388842-26-9
Molecular Formula:C₁₃H₉F₆N₅O
Molecular Weight:365.238
Hs Code.:

Synonyms:(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

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Technology Process of (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

There total 7 articles about (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₁₇F₆N₅O₃

: 1388842-26-9
(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

Guidance literature:: With trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield:

: 1388842-52-1
(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic (isobutyl carbonic) anhydride

: 1388842-26-9
(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

Guidance literature:: With hydrazine hydrate; at 0 ℃; for 0.5h;

Reference yield:

: 1388842-44-1
(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid

: 1388842-26-9
(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine / tetrahydrofuran / 0.5 h / 0 °C

2: hydrazine hydrate / 0.5 h / 0 °C

With 4-methyl-morpholine; hydrazine hydrate; In tetrahydrofuran;