3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

Base Information

Chemical Name:3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole
CAS No.:723242-26-0
Molecular Formula:C₃₁H₃₉N₃O
Molecular Weight:469.67
Hs Code.:

Synonyms:3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

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Chemical Property of 3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

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Technology Process of 3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

There total 1 articles about 3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 37942-07-7
3,5-di-tert-butyl-2-hydroxybenzaldehyde

: 2-(1H-indol-3-yl)-N-(pyridin-2-ylmethyl)ethanamine

: 723242-26-0
3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

Guidance literature:: With sodium cyanoborohydride; In methanol; for 6h;
DOI:10.1021/ja031587v

Reference yield:

: 723242-26-0
3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

: Pd(3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole radical cation-,kappa.C₂)Cl⁽¹⁺⁾

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetonitrile

2: Ce⁽⁴⁺⁾ / N,N-dimethyl-formamide

With triethylamine; Ce⁽⁴⁺⁾; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja031587v

Reference yield:

: 723242-26-0
3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole

: 723242-25-9
Pd(3-[N-2-pyridylmethyl-N-2-hydroxy-3,5-di(tert-butyl)benzylamino]ethylindole(1-)-κC2)Cl

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane; acetonitrile

2: dichloromethane; acetonitrile

With triethylamine; In dichloromethane; acetonitrile;
DOI:10.1021/ja031587v