(1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

Base Information

Chemical Name:(1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine
CAS No.:187993-44-8
Molecular Formula:C₂₇H₂₆N₂O₄
Molecular Weight:442.514
Hs Code.:

Synonyms:(1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

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Chemical Property of (1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

Chemical Property:

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Technology Process of (1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

There total 3 articles about (1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 187993-99-3
(4R)-4-(4,5-diphenyloxazol-2-yl)-4-benzyloxycarbonylamino-1-butene

: 7722-84-1
dihydrogen peroxide

: 280-64-8
9-bora-bicyclo[3.3.1]nonane

: 187993-44-8
(1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

Guidance literature:: With sodium hydroxide; In tetrahydrofuran;

Reference yield:

: 187993-99-3
(4R)-4-(4,5-diphenyloxazol-2-yl)-4-benzyloxycarbonylamino-1-butene

: 187993-44-8
(1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; water; at 0 - 20 ℃; for 5h;

Reference yield:

: (5R)-5-(4,5-diphenyloxazol-2-yl)pyrrolidin-2-one

: 501-53-1,94274-21-2
benzyl chloroformate

: 187993-44-8
(1R)-N-benzyloxycarbonyl-4-hydroxy-1-(4,5-diphenyloxazol-2-yl)butylamine

Guidance literature:: (5R)-5-(4,5-diphenyloxazol-2-yl)pyrrolidin-2-one; benzyl chloroformate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

With sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

With sodium tetrahydroborate; chloroformic acid ethyl ester; triethylamine; more than 3 stages;