D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Base Information

Chemical Name:D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph
CAS No.:1026159-93-2
Molecular Formula:C₃₆H₄₆N₄O₅
Molecular Weight:614.785
Hs Code.:

D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH<sub>2</sub>Ph

Synonyms:D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Suppliers and Price of D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

There total 7 articles about D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1027545-12-5
L-Pip-D-Phe-L-Pro-OCH₂Ph

: 1026159-93-2
D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N,N-diisopropylethylamine (DIEA), bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl), 2.) N,N-diisopropylethylamine (DIEA) / 1.) CH₂Cl₂, 1.5 h, 2.) CH₂Cl₂, 0 deg C, 16 h

2: 52 percent / NaH / dimethylformamide / 0.75 h / 0 °C

3: 98percent aq. formic acid / 2 h / Ambient temperature

With formic acid; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;
DOI:10.1021/jm00099a019

Reference yield:

: 134526-69-5,132910-78-2
tert-butoxycarbonyl-D-piperidine-2-carboxaldehyde

: 1026159-93-2
D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N,N-diisopropylethylamine (DIEA), bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl), 2.) N,N-diisopropylethylamine (DIEA) / 1.) CH₂Cl₂, 1.5 h, 2.) CH₂Cl₂, 0 deg C, 16 h

2: 52 percent / NaH / dimethylformamide / 0.75 h / 0 °C

3: 98percent aq. formic acid / 2 h / Ambient temperature

With formic acid; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;
DOI:10.1021/jm00099a019

Reference yield:

: 96935-61-4
H-D-Phe-L-Pro-OCH₂Ph hydrochloride

: 1026159-93-2
D-Pip-L-Pip-D-(N-allyl)Phe-L-Pro-OCH₂Ph

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / N,N-diisopropylethylamine (DIEA) / CH₂Cl₂ / 2 h / pH 8

2: diethylamine / acetonitrile / Ambient temperature

3: 1.) N,N-diisopropylethylamine (DIEA), bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl), 2.) N,N-diisopropylethylamine (DIEA) / 1.) CH₂Cl₂, 1.5 h, 2.) CH₂Cl₂, 0 deg C, 16 h

4: 52 percent / NaH / dimethylformamide / 0.75 h / 0 °C

5: 98percent aq. formic acid / 2 h / Ambient temperature

With formic acid; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydride; diethylamine; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00099a019