1,5-Anhydro-1-phenethylsorbitol tetraacetate

Base Information

• Chemical Name: 1,5-Anhydro-1-phenethylsorbitol tetraacetate
• CAS No.: 114421-40-8
• Molecular Formula: C₂₂H₂₈O₉
• Molecular Weight: 436.459
• Mol file: 114421-40-8.mol

Synonyms:1,5-Anhydro-1-phenethylsorbitol tetraacetate

Chemical Property of 1,5-Anhydro-1-phenethylsorbitol tetraacetate

Chemical Property:

• PSA: 114.43000
• Density: 1.23
• LogP: 1.74480

Purity/Quality:

98%min ^*data from raw suppliers

1,5-ANHYDRO-1-PHENETHYLSORBITOL TETRAACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5-Anhydro-1-phenethylsorbitol tetraacetate

There total 15 articles about 1,5-Anhydro-1-phenethylsorbitol tetraacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-phenyl-2-(2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyl)ethanone → 2,3,4,6-O-tetra-acetyl-1-deoxy-1-(2-phenylethyl)-β-D-glucopyranose (85505-09-5,114421-40-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In methanol; at 20 ℃; for 18h;

DOI:10.3184/174751916X14762012580355

Reference yield: 87.0%

1-phenyl-D-glycero-D-gulo-3,7-anhydro-1,2-dideoxy-octitol (121421-11-2) + acetyl chloride (75-36-5) → C24H30O10 (1134621-10-5) + 2,3,4,6-O-tetra-acetyl-1-deoxy-1-(2-phenylethyl)-β-D-glucopyranose (85505-09-5,114421-40-8)

Guidance literature:

With trifluorormethanesulfonic acid; at 0 ℃; for 0.333333h;

DOI:10.3987/COM-08-S(F)39

Reference yield: 85.0%

1-deoxy-1-(C-2',4',6'-trimethoxyphenyl)-2,3,4,6-tetra-O-benzyl-D-glucopyranose → α-1-deoxy-1-(C-1'-phenethyl)-2,3,4,6-tetra-O-acetyl-D-glucopyranose (85422-91-9,114421-40-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 25 ℃; for 12h;

DOI:10.1021/ja00300a036

upstream raw materials:

phenethylmagnesium bromide

2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

acetic anhydride

2-(2,3,4,6-Tetra-O-benzyl-α,β-D-glucopyranosyl)acetophenon