6-Bromobenzo[d]isothiazole-3-carboxamide

Base Information

• Chemical Name: 6-Bromobenzo[d]isothiazole-3-carboxamide
• CAS No.: 947691-81-8
• Molecular Formula: C₈H₅BrN₂OS
• Molecular Weight: 257.111
• Mol file: 947691-81-8.mol

Synonyms:6-Bromobenzo[d]isothiazole-3-carboxamide;

Chemical Property of 6-Bromobenzo[d]isothiazole-3-carboxamide

Chemical Property:

• Refractive Index: 1.744
• Boiling Point: 368.8 °C at 760 mmHg
• Flash Point: 176.9 °C
• PSA: 84.22000
• Density: 1.821
• LogP: 2.85800

Purity/Quality:

98%Min ^*data from raw suppliers

6-Bromobenzo[d]isothiazole-3-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Bromobenzo[d]isothiazole-3-carboxamide

There total 1 articles about 6-Bromobenzo[d]isothiazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

6-bromobenzo[b]thiophene-2,3-dione (73655-14-8) → 6-bromo-1,2-benzothiazole-3-carboxamide (947691-81-8)

Guidance literature:

With ammonium hydroxide; dihydrogen peroxide; In water; at 5 - 20 ℃;

Reference yield: 91.0%

6-bromo-1,2-benzothiazole-3-carboxamide (947691-81-8) → 6-bromo-benzo[d]isothiazole-3-carboxylic acid (677304-75-5)

Guidance literature:

6-bromo-1,2-benzothiazole-3-carboxamide; With water; sodium hydroxide; In methanol; Reflux;

With hydrogenchloride; In methanol; water;

upstream raw materials:

6-bromobenzo[b]thiophene-2,3-dione

Downstream raw materials:

6-bromo-benzo[d]isothiazole-3-carboxylic acid

Refernces

• 1、 -. "CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS". Page/Page column 66. . Retrieved 2010/11/28.