Bredemolic acid

Base Information

• Chemical Name: Bredemolic acid
• CAS No.: 5957-40-4
• Molecular Formula: C₃₀H₄₈O₄
• Molecular Weight: 472.709
• Mol file: 5957-40-4.mol

Synonyms:Bredemolicacid (6CI); Olean-12-en-28-oic acid, 2b,3a-dihydroxy- (7CI,8CI)

Chemical Property of Bredemolic acid

Chemical Property:

• PSA: 77.76000
• LogP: 6.20440

Purity/Quality:

98%min ^*data from raw suppliers

BREDEMOLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bredemolic acid

There total 20 articles about Bredemolic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl (2α,3β)-2,3-dihydroxy-olean-12-en-28-oate (464876-77-5) → maslinic acid (4373-41-5,5957-40-4,26563-68-8,26707-60-8,120707-84-8,125137-38-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.bmcl.2005.10.014

Reference yield: 70.0%

methyl maslinate (22425-82-7) → maslinic acid (4373-41-5,5957-40-4,26563-68-8,26707-60-8,120707-84-8,125137-38-4)

Guidance literature:

With lithium; In ethylenediamine; for 4h; Heating;

Reference yield: 48.0%

(2α)-2-hydroxy-3-oxo-olean-12-en-28-oic acid (73584-62-0) + acetone (67-64-1) → maslinic acid (4373-41-5,5957-40-4,26563-68-8,26707-60-8,120707-84-8,125137-38-4) + (2α,3α)-(isopropylidenedioxy)olean-12-en-28-oic acid

Guidance literature:

(2α)-2-hydroxy-3-oxo-olean-12-en-28-oic acid; With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 ℃; for 1h;

acetone; With sulfuric acid; at 0 - 60 ℃; for 0.5h;

DOI:10.1016/j.tet.2015.09.037

upstream raw materials:

methyl maslinate

2α,3β-diacetoxyoleane 12-ene-28-carboxylic acid

3-acetylmaslinic acid (TARB-2)

benzyl (2α,3β)-2,3-dihydroxy-olean-12-en-28-oate

Downstream raw materials:

benzyl (2α,3β)-2,3-di-acetoxy-olean-12-en-28-oate

C₄₀H₅₈O₅

C₄₃H₆₂O₆

C₄₁H₆₀O₅