N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N₂-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine

Base Information

• Chemical Name: N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N₂-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine
• CAS No.: 898280-69-8
• Molecular Formula: C₂₁H₂₁N₇O
• Molecular Weight: 387.444

Synonyms:N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N₂-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine

Chemical Property of N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N₂-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine

Chemical Property:

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Technology Process of N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N₂-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine

There total 1 articles about N₄-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N₂-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2-chloro-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylpyrimidin-4-amine (851435-39-7) + 1-(3-phenyl-1,2-oxazol-5-yl)methanamine (54408-35-4) → N4-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methyl-N2-(3-phenylisoxazol-5-ylmethyl)pyrimidine-2,4,6-triamine (898280-69-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 160 ℃; for 8h;

upstream raw materials:

2-chloro-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-methylpyrimidin-4-amine

1-(3-phenyl-1,2-oxazol-5-yl)methanamine

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