54408-35-4

Usage

Uses

Used in Pharmaceutical Industry:
(3-PHENYL-5-ISOXAZOLYL)METHANAMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique molecular structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, (3-PHENYL-5-ISOXAZOLYL)METHANAMINE serves as a precursor in the synthesis of agrochemicals. Its properties allow for the creation of compounds with pesticidal or herbicidal activities, contributing to crop protection and yield enhancement.
Used in Organic Chemistry Research:
(3-PHENYL-5-ISOXAZOLYL)METHANAMINE is utilized as a research compound in organic chemistry. Its diverse reactivity and molecular structure make it an important tool for exploring new chemical reactions and synthesizing novel organic compounds.
Used in Material Science:
(3-PHENYL-5-ISOXAZOLYL)METHANAMINE is employed in the development of new materials. Its unique properties can be leveraged to create advanced materials with specific characteristics for various applications, such as in electronics, coatings, or polymers.

InChI:InChI=1/C10H10N2O/c11-7-9-6-10(12-13-9)8-4-2-1-3-5-8/h1-6H,7,11H2

Upstream product

• 873-67-6 benzonitrile oxide 
• 107-11-9 1-amino-2-propene 
• 1011-37-6 3-phenyl-5-chloromethyl-1,2,4-oxadiazole 
• 90924-12-2 3-phenyl-5-hydroxymethylisoxazole 
• 2039-50-1 5-bromomethyl-3-phenyl-isoxazole 
• 100-52-7 benzaldehyde 
• 478048-73-6 C₁₈H₁₂N₂O₃ 
• 932-90-1 Benzaldoxime 
• 698-16-8 benzohydroximoyl chloride 
• 942935-99-1 5-(azidomethyl)-3-phenylisoxazole 

Downstream Products

• 13608-54-3 N-(3-phenyl-5-isoxazolinyl)methylbenzamidoxime 
• 339016-92-1 4-chloro-N-((3-phenylisoxazol-5-yl)methyl)benzenesulfonamide 
• 1459184-17-8 (6,7-bis(2-methoxyethoxy))-4-((3-phenyl-isoxazol-5-yl)-methylamino)quinazoline 
• 1459184-09-8 (6,7-bis(2-methoxyethoxy))-4-((3-phenyl-isoxazol-5-yl)methoxy)quinazoline 
• 1342304-71-5 2-chloro-4-isopropylamino-6-((3-phenyl-1,2-oxazol-5-yl)methylamino)-1,3,5-triazine 

Relevant academic research and scientific papers

Rifamycin derivatives active against pathogenic rapidly-growing mycobacteria

Infections due to rapidly growing mycobacteria (RGM), and in particular the RGM species Mycobacterium abscessus (Mab), are very difficult to treat and reports on novel therapeutic options are scarce. A hallmark of all pathogenic RGM species is their resis

Quinazoline derivatives preparation method and use thereof

The invention discloses a quinazoline derivative shown in formula (I) which is described in the specification and a salt thereof. In the formula, Z represents -NH- and -O-, R1 and R2 represent C1-3 alkoxy groups or hydrogen, R3 is selected from the group consisting of 4-fluoro-, 4-chloro-, 2-chloro-, 4-bromo-, 2, 4-dichloro-, 4-methyl, 4-methoxy, hydrogen, 4-trifluoromethyl and 2,4-dimethoxy. The invention relates to a preparation method and application of the compound shown in the formula (I) and the salt thereof. The compound or the salt thereof has strong inhibitory activity on colorectal cancer cell strains HCT-116, human lung cancer cell strains A549 and breast cancer cell strains MCF-7. The compound has wide spectrum antitumor activity and can be used as a drug or lead compound for treatment of diseases like tumors and cancers.

Synthesis and biological evaluation of isoxazolyl-sulfonamides: A non-cytotoxic scaffold active against Trypanosoma cruzi, Leishmania amazonensis and Herpes Simplex Virus

In this study we report the synthesis, characterization, biological evaluation, and druglikeness assessment of a series of 20 novel isoxazolyl-sulfonamides, obtained by a four-step synthetic route. The compounds had their activity against Trypanosoma cruz

Ferrocene derivatives, preparation method and use thereof

The invention discloses ferrocene derivatives as shown in a formula I in the specification and salts thereof, wherein Z is O or NH; R is selected from hydrogen, fluorine, chlorine, bromine, methyl, methoxyl and trifluoromethyl; n is an integer ranging fro

Quinazoline derivatives and their use

The present invention provides a quinazoline compound shown in formula (I), or pharmaceutically acceptable salt thereof. R1, R2 and R7 are independently and respectively selected from hydrogen, C1-6 alkyl, C1-6 alkoxy, halogenate C1-6 alkyl, halogenate C1

Thiophene [2, 3 - d] pyrimidine derivatives, their preparation and use thereof

The invention provides a thiophene [2, 3-d] pyrimidine derivative containing isoxazole heterocycle shown by formula (I) or a pharmaceutically accepted salt thereof, wherein R1 and R2 are respectively selected from hydrogen, C1-6 alkyl, C1-6 alkoxy, haloge

THIOPHENE [2, 3-D]PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF

This invention provides thieno[2,3-d]pyrimidine derivatives containing isoxazole heterocycle represented by formula (I), or pharmaceutically acceptable salts thereof Wherein: R1 and R2 may be the same or different and is independentl

QUINAZOLINE DERIVATIVE AND APPLICATION THEREOF

This invention provides a class of quinazoline compounds, as represented by formula (I), and their pharmaceutically acceptable salts, wherein: each of R1 and R2 independently, is selected from H, C1-C6 alkoxy, h

QUINAZOLINE DERIVATIVE AND APPLICATION THEREOF

This invention provides a class of quinazoline compounds, as represented by formula (I), and their pharmaceutically acceptable salts, wherein: each of R1 and R2 independently, is selected from H, C1-C6 alkoxy, h

Design, synthesis and antibacterial activity of novel N-formylhydroxylamine derivatives as PDF inhibitors

A new series of N-formylhydroxylamines 11a-i have been synthesized through a multi-step protocol starting from diethyl malonate. These compounds have been structurally characterized by IR, 1H NMR and HRMS. All the synthesized compounds 11a-i have been screened for antibacterial activities. All the compounds are found to exhibit potent in vitro inhibitory activity against Staphylococcus aureus and relatively weak antibacterial activity against Klebsiella pneumoniae.