54408-35-4

Basic information

• Product Name: (3-PHENYL-5-ISOXAZOLYL)METHANAMINE
• Synonyms: C-(3-PHENYL-ISOXAZOL-5-YL)-METHYLAMINE;3-PHENYL-ISOXAZOL-5-YL-METHYLAMINE;(3-PHENYL-5-ISOXAZOLYL)METHANAMINE;5-(Aminomethyl)-3-phenylisoxazole 97%;5-(Aminomethyl)-3-phenylisoxazole;(3-phenylisoxazol-5-yl)methanamine;1-(3-phenylisoxazol-5-yl)methanamine(SALTDATA: HCl);5-(Aminomethyl)-3-phenylisoxazole97%
• CAS NO: 54408-35-4
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Mol File: 54408-35-4.mol
• Article Data: 17

Chemical Properties

• Melting Point: 51-53°C
• Boiling Point: 342 °C at 760 mmHg
• Flash Point: 160.7 °C
• Appearance: /
• Density: 1.155±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 7.73E-05mmHg at 25°C
• Refractive Index: 1.5670 (589.3 nm 20℃)
• Storage Temp.: 2-8°C
• PKA: 7.82±0.29(Predicted)
• CAS DataBase Reference: (3-PHENYL-5-ISOXAZOLYL)METHANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-PHENYL-5-ISOXAZOLYL)METHANAMINE(54408-35-4)
• EPA Substance Registry System: (3-PHENYL-5-ISOXAZOLYL)METHANAMINE(54408-35-4)

Safety Data

• Hazard Codes: C,T
• Statements: 34-25
• Safety Statements: 26-36/37/39-45
• RIDADR: 3259
• HazardClass: IRRITANT
• Hazardous Substances Data: 54408-35-4(Hazardous Substances Data)

Usage

General Description

(3-Phenyl-5-isoxazolyl)methanamine is a chemical compound with the molecular formula C9H9N3O. It is a member of the isoxazole class of heterocyclic compounds, which are known for their diverse pharmacological activities. (3-PHENYL-5-ISOXAZOLYL)METHANAMINE is utilized as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Its reactivity and unique molecular structure make it a valuable precursor for the development of new drugs and materials. The compound's potential applications in research and industry highlight its importance in the field of organic chemistry.

InChI:InChI=1/C10H10N2O/c11-7-9-6-10(12-13-9)8-4-2-1-3-5-8/h1-6H,7,11H2

Upstream product

• 873-67-6 benzonitrile oxide 
• 107-11-9 1-amino-2-propene 
• 1011-37-6 3-phenyl-5-chloromethyl-1,2,4-oxadiazole 
• 90924-12-2 3-phenyl-5-hydroxymethylisoxazole 
• 100-52-7 benzaldehyde 
• 478048-73-6 C₁₈H₁₂N₂O₃ 
• 2039-50-1 5-bromomethyl-3-phenyl-isoxazole 
• 698-16-8 benzohydroximoyl chloride 
• 932-90-1 Benzaldoxime 
• 942935-99-1 5-(azidomethyl)-3-phenylisoxazole 

Downstream Products

• 13608-54-3 N-(3-phenyl-5-isoxazolinyl)methylbenzamidoxime 
• 66046-40-0 5-isothiocyanatomethyl-3-phenylisoxazole 
• 339016-92-1 4-chloro-N-((3-phenylisoxazol-5-yl)methyl)benzenesulfonamide 
• 1459184-17-8 (6,7-bis(2-methoxyethoxy))-4-((3-phenyl-isoxazol-5-yl)-methylamino)quinazoline 
• 1459184-09-8 (6,7-bis(2-methoxyethoxy))-4-((3-phenyl-isoxazol-5-yl)methoxy)quinazoline 
• 1342304-71-5 2-chloro-4-isopropylamino-6-((3-phenyl-1,2-oxazol-5-yl)methylamino)-1,3,5-triazine 

Relevant articles and documents

Rifamycin derivatives active against pathogenic rapidly-growing mycobacteria

Infections due to rapidly growing mycobacteria (RGM), and in particular the RGM species Mycobacterium abscessus (Mab), are very difficult to treat and reports on novel therapeutic options are scarce. A hallmark of all pathogenic RGM species is their resis

Synthesis and biological evaluation of isoxazolyl-sulfonamides: A non-cytotoxic scaffold active against Trypanosoma cruzi, Leishmania amazonensis and Herpes Simplex Virus

In this study we report the synthesis, characterization, biological evaluation, and druglikeness assessment of a series of 20 novel isoxazolyl-sulfonamides, obtained by a four-step synthetic route. The compounds had their activity against Trypanosoma cruz

Quinazoline derivatives and their use

The present invention provides a quinazoline compound shown in formula (I), or pharmaceutically acceptable salt thereof. R1, R2 and R7 are independently and respectively selected from hydrogen, C1-6 alkyl, C1-6 alkoxy, halogenate C1-6 alkyl, halogenate C1