C₅₄H₈₁N₂O₁₅P

Base Information

• Chemical Name: C₅₄H₈₁N₂O₁₅P
• CAS No.: 1277177-80-6
• Molecular Formula: C₅₄H₈₁N₂O₁₅P
• Molecular Weight: 1029.22
• Mol file: 1277177-80-6.mol

Synonyms:C₅₄H₈₁N₂O₁₅P

Chemical Property of C₅₄H₈₁N₂O₁₅P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₄H₈₁N₂O₁₅P

There total 15 articles about C₅₄H₈₁N₂O₁₅P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C57H84N3O15P (1277177-79-3) → C54H81N2O15P (1277177-80-6)

Guidance literature:

C₅₇H₈₄N₃O₁₅P; With propylamine; In methanol; for 0.25h;

In methanol;

DOI:10.1002/ejoc.201001264

Reference yield:

6-Benzyloxycarbonylamino-hexanoic acid (S)-2-hydroxy-3-(4-methoxy-benzyloxy)-propyl ester (180894-76-2) → C54H81N2O15P (1277177-80-6)

Guidance literature:

Multi-step reaction with 6 steps

1.1: pyridine; dmap / dichloromethane

2.1: palladium 10% on activated carbon; hydrogen / methanol

3.1: dmap; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine / dichloromethane / Inert atmosphere

4.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water

5.1: 4,5-dicyano-1H-imidazole / dichloromethane; acetonitrile / 3 h / Inert atmosphere

5.2: 20 °C / Cooling with ice

6.1: propylamine / methanol / 0.25 h

6.2: Amberlite IR-120

With pyridine; propylamine; dmap; 4,5-dicyano-1H-imidazole; palladium 10% on activated carbon; hydrogen; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1002/ejoc.201001264

Reference yield:

C41H63NO8 → C54H81N2O15P (1277177-80-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: palladium 10% on activated carbon; hydrogen / methanol

2.1: dmap; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine / dichloromethane / Inert atmosphere

3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water

4.1: 4,5-dicyano-1H-imidazole / dichloromethane; acetonitrile / 3 h / Inert atmosphere

4.2: 20 °C / Cooling with ice

5.1: propylamine / methanol / 0.25 h

5.2: Amberlite IR-120

With propylamine; dmap; 4,5-dicyano-1H-imidazole; palladium 10% on activated carbon; hydrogen; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1002/ejoc.201001264

upstream raw materials:

6-Benzyloxycarbonylamino-hexanoic acid (S)-2-hydroxy-3-(4-methoxy-benzyloxy)-propyl ester

C₂₁H₄₀N₃O₆P

C₁₈H₁₄O₄

propargyloxybenzophenone carboxylic acid

Downstream raw materials:

C₄₅H₆₅N₂O₁₃P

Refernces