2-(3-Methoxy-4-methylphenyl)ethan-1-amine

Base Information

Chemical Name:2-(3-Methoxy-4-methylphenyl)ethan-1-amine
CAS No.:18149-16-1
Molecular Formula:C₁₀H₁₅NO
Molecular Weight:165.235
Hs Code.:
ChEMBL ID:CHEMBL4558500
DSSTox Substance ID:DTXSID00515245
Wikidata:Q82376029
Mol file:18149-16-1.mol

Synonyms:18149-16-1;2-(3-METHOXY-4-METHYLPHENYL)ETHANAMINE;2-(3-methoxy-4-methylphenyl)ethan-1-amine;SCHEMBL3780939;CHEMBL4558500;DTXSID00515245;PXSYKFKOKXYQRH-UHFFFAOYSA-N;AKOS006293315;EN300-84414;Z1198167712

Suppliers and Price of 2-(3-Methoxy-4-methylphenyl)ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3-methoxy-4-methylphenyl)ethan-1-amine
100mg
$ 240.00

TRC
2-(3-methoxy-4-methylphenyl)ethan-1-amine
10mg
$ 45.00

American Custom Chemicals Corporation
2-(3-METHOXY-4-METHYLPHENYL)ETHANAMINE 95.00%
2.5G
$ 1499.48

American Custom Chemicals Corporation
2-(3-METHOXY-4-METHYLPHENYL)ETHANAMINE 95.00%
1G
$ 998.08

AK Scientific
2-(3-Methoxy-4-methylphenyl)ethan-1-amine
500mg
$ 561.00

Total 4 raw suppliers

Chemical Property of 2-(3-Methoxy-4-methylphenyl)ethan-1-amine

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:165.115364102
Heavy Atom Count:12
Complexity:127

Purity/Quality:

99% ^*data from raw suppliers

2-(3-methoxy-4-methylphenyl)ethan-1-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)CCN)OC

Technology Process of 2-(3-Methoxy-4-methylphenyl)ethan-1-amine

There total 10 articles about 2-(3-Methoxy-4-methylphenyl)ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1391042-74-2
3-methoxy-4-methyl-1-[(E)-2′-nitrovinyl]benzene

: 18149-16-1
1′-(3-methoxy-4-methylphenyl)ethyl-2′-amine

Guidance literature:: With sodium tetrahydroborate; boron trifluoride diethyl etherate; In tetrahydrofuran; for 6.5h; Inert atmosphere; Reflux;
DOI:10.1021/acs.joc.8b02888

Reference yield:

: 3556-83-0
methyl 4-methyl-3-methoxybenzoate

: 18149-16-1
1′-(3-methoxy-4-methylphenyl)ethyl-2′-amine

Guidance literature:: Multi-step reaction with 4 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

2: manganese(IV) oxide / chloroform / 18 h / 20 °C

3: ammonium acetate / toluene / 18 h / Inert atmosphere; Reflux

4: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 6.5 h / Inert atmosphere; Reflux

With manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; ammonium acetate; In tetrahydrofuran; chloroform; toluene;
DOI:10.1021/acs.joc.8b02888