2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone

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Chemical Name:2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone
CAS No.:938180-68-8
Molecular Formula:C₃₀H₂₆FN₃O₂
Molecular Weight:479.554
Hs Code.:

Synonyms:2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone

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Chemical Property of 2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone

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Technology Process of 2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone

There total 1 articles about 2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 938177-13-0
5-bromo-2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-4(3H)-pyrimidinone

: 135884-31-0
N-boc-2-pyrroleboronic acid

: 938180-68-8
2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; water; at 150 ℃; for 0.361111h; Microwave;

Reference yield: 47.0%

: 938180-68-8
2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone

: 74-88-4
methyl iodide

: 938180-69-9
2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-5-(1-methyl-1H-pyrrol-2-yl)-3-(2-phenylethyl)-4(3H)-pyrimidinone

Guidance literature:: 2-{3-fluoro-2-[(phenylmethyl)oxy]phenyl}-6-methyl-3-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-4(3H)-pyrimidinone; methyl iodide; With caesium carbonate; In N,N-dimethyl-formamide;

With water; In N,N-dimethyl-formamide;