N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide

Base Information

• Chemical Name: N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide
• CAS No.: 474328-45-5
• Molecular Formula: C₂₁H₃₀N₂O₂S
• Molecular Weight: 374.547
• Mol file: 474328-45-5.mol

Synonyms:N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide

Chemical Property of N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide

There total 1 articles about N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-tosyl-4-amino-2,6-diisopropyl aniline (474328-44-4) → N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide (474328-45-5)

Guidance literature:

With sodium tetrahydroborate; sulfuric acid; at -10 - 20 ℃;

DOI:10.1002/1521-3765(20020703)8:13<2847::AID-CHEM2847>3.0.CO;2-M

Reference yield: 81.0%

N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide (474328-45-5) → 3,5-diisopropyl-N,N-dimethylbenzene-1,4-diamine

Guidance literature:

With sulfuric acid; at 40 ℃; for 6h;

DOI:10.1002/1521-3765(20020703)8:13<2847::AID-CHEM2847>3.0.CO;2-M

Reference yield:

N-(4-dimethylamino-2,6-diisopropyl-phenyl)-4-methyl-benzenesulfonamide (474328-45-5) → N,N'-bis-(4-dimethylamino-2,6-diisopropyl-phenyl)-isophthalamide

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / aq. H₂SO₄ / 6 h / 40 °C

2: 78 percent / Et₃N / CH₂Cl₂ / 12 h

With sulfuric acid; triethylamine; In dichloromethane;

DOI:10.1002/1521-3765(20020703)8:13<2847::AID-CHEM2847>3.0.CO;2-M

upstream raw materials:

formaldehyd

N-tosyl-4-amino-2,6-diisopropyl aniline