(S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid

Base Information

• Chemical Name: (S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid
• CAS No.: 106910-79-6
• Molecular Formula: C12H13NO4
• Molecular Weight: 235.24
• Hs Code.: 2934999090
• Mol file: 106910-79-6.mol

Synonyms:3-Morpholinecarboxylicacid, 5-oxo-4-(phenylmethyl)-, (?à)-;4-Benzyl-5-oxomorpholine-3-carboxylic acid;

Chemical Property of (S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid

Chemical Property:

• Vapor Pressure: 4.28E-11mmHg at 25°C
• Melting Point: 170-173°C
• Refractive Index: 1.587
• Boiling Point: 506.8 °C at 760 mmHg
• PKA: 3.22±0.20(Predicted)
• Flash Point: 260.3 °C
• PSA: 66.84000
• Density: 1.339 g/cm³
• LogP: 0.43650
• Storage Temp.: Refrigerator
• Solubility.: Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

(S)-(+)-4-Benzylmorpholin-5-one-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid

There total 7 articles about (S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

(RS)-N-benzyl-N-chloroacetylserine (106910-78-5) → (RS)-4-benzyl-5-oxomorpholine-3-carboxylic acid (106910-79-6)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; for 3h; Heating;

Reference yield: 35.0%

(RS)-N-benzylserine (106910-76-3) + chloroacetyl chloride (79-04-9) → (RS)-4-benzyl-5-oxomorpholine-3-carboxylic acid (106910-79-6)

Guidance literature:

With sodium hydroxide; In water; 0 deg C, 30 min, 30-33 deg C, 2 h;

Reference yield:

(S)-2-(benzylamino)-3-hydroxypropanoic acid (106910-76-3,106910-77-4,17136-45-7) + chloroacetyl chloride (79-04-9) → (RS)-4-benzyl-5-oxomorpholine-3-carboxylic acid (106910-79-6)

Guidance literature:

(S)-2-(benzylamino)-3-hydroxypropanoic acid; chloroacetyl chloride; With potassium carbonate; In tetrahydrofuran; water; at 0 ℃; for 0.5h;

With sodium hydroxide; In tetrahydrofuran; water; at -5 - 0 ℃; pH=> 13;

With hydrogenchloride; In water; at -10 ℃; pH=< 2; Product distribution / selectivity;

upstream raw materials:

(RS)-N-benzyl-N-chloroacetylserine

(RS)-N-benzylserine

chloroacetyl chloride

benzaldehyde

Downstream raw materials:

ethyl (RS)-4-benzyl-5-oxomorpholine-3-carboxylate

(RS)-4-benzyl-3-hydroxymethylmorpholin-5-one

4-benzyl-3-(hydroxymethyl)morpholine

methyl (RS)-N-benzyl-5-oxomorpholine-3-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 106910-79-6 (S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send