N-1-Benzyl-3-ethylpiperazine

Base Information

• Chemical Name: N-1-Benzyl-3-ethylpiperazine
• CAS No.: 313657-25-9
• Molecular Formula: C13H20 N2
• Molecular Weight: 204.31
• Hs Code.: 2933599090
• Mol file: 313657-25-9.mol

Synonyms:1-Benzyl-3-ethylpiperazine

Chemical Property of N-1-Benzyl-3-ethylpiperazine

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Boiling Point: 298.8°Cat760mmHg
• Flash Point: 115.2°C
• PSA: 15.27000
• Density: 0.975g/cm³
• LogP: 2.13710

Purity/Quality:

97% ^*data from raw suppliers

1-benzyl-3-ethylpiperazine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-1-Benzyl-3-ethylpiperazine

There total 1 articles about N-1-Benzyl-3-ethylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

CHCl3/MeOH + benzyl bromide (100-39-0) + 2-ethylpiperazine (13961-37-0) → 1-benzyl-3,3-ethylidenepiperazine (313657-25-9,347195-55-5)

Guidance literature:

With ammonium hydroxide; In chloroform; N,N-dimethyl-formamide;

Reference yield:

2,3-dichloropyrazine (4858-85-9) + 1-benzyl-3,3-ethylidenepiperazine (313657-25-9,347195-55-5) → 4-benzyl-1-(3-chloro-2-pyrazinyl)-2-ethylpiperazine (313657-26-0)

Guidance literature:

With potassium carbonate; In n-heptane; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

1-benzyl-3,3-ethylidenepiperazine (313657-25-9,347195-55-5) + p-toluenesulfonyl chloride (98-59-9) → C20H26N2O2S + C20H26N2O2S

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 23 ℃; for 18h; Overall yield = 10%; Overall yield = 0.004 g;

DOI:10.1021/acs.joc.6b01884

upstream raw materials:

benzyl bromide

2-ethylpiperazine

Downstream raw materials:

4-benzyl-1-(3-chloro-2-pyrazinyl)-2-ethylpiperazine

Refernces