(4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

Base Information

Chemical Name:(4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate
CAS No.:293299-44-2
Molecular Formula:C₁₇H₂₄BrNO₅S
Molecular Weight:434.351
Hs Code.:

Synonyms:(4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

Suppliers and Price of (4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

There total 2 articles about (4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: (4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-ol

: 124-63-0
methanesulfonyl chloride

: 293299-44-2
(4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

Guidance literature:: With triethylamine; In tetrahydrofuran; at -78 - 0 ℃; for 0.5h;
DOI:10.1021/jo016320y

Reference yield:

: 253675-99-9
Methyl (4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-enoate

: 293299-44-2
(4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / DIBAL-H / CHCl₃; toluene / 2 h / -78 - 0 °C

2: 89 percent / Et₃N / tetrahydrofuran / 0.5 h / -78 - 0 °C

With diisobutylaluminium hydride; triethylamine; In tetrahydrofuran; chloroform; toluene;
DOI:10.1021/jo016320y

Reference yield: 82.0%

: 293299-44-2
(4S,2Z)-2-bromo-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpent-2-en-1-yl methylsulfonate

: (4S)-4-[N-(tert-butoxycarbonyl)amino]-5-phenylpenta-1,5-diene

Guidance literature:: With diethylzinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1016/S0040-4039(00)00790-5