dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

Base Information

Chemical Name:dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate
CAS No.:1314756-90-5
Molecular Formula:C₂₄H₃₉O₈P
Molecular Weight:486.543
Hs Code.:

Synonyms:dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

Suppliers and Price of dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

There total 1 articles about dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 807365-26-0
((S)-4-Benzyloxy-5-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-3,3-dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester

: 1314756-90-5
dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1039/c1cc12332g

Reference yield:

: 1314756-90-5
dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

: C₃₁H₅₆O₅Si₂

: 1314756-91-6
(E)-(2S,10R)-2-benzyloxy-1-{(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl[1,3]dioxan-4-yl}-11-(4-methoxy-benzyloxy)-3,3-dimethyl-10-triethylsilyloxy-8-[(Z)-2-tri-isopropylsilyloxyethylidene]undec-5-en-4-one

Guidance literature:: dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate; With 0.8H₂O*BaH₂O₂; In tetrahydrofuran; at 20 ℃; for 0.5h;

C₃₁H₅₆O₅Si₂; In tetrahydrofuran; water; at 20 ℃; for 16h;
DOI:10.1039/c7ob02129a

Reference yield:

: 1314756-90-5
dimethyl (4S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-3,3-dimethyl-2-oxopentylphosphonate

: 1314756-94-9
(S)-4-benzyloxy-5-[(4R,6S)-6-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxan-4-yl]-1-{(2S,6R)-6-(4-methoxy-benzyloxymethyl)-4-[(Z)-2-triisopropylsilyloxyethylidene]tetrahydropyran-2-yl}-3,3-dimethylpentan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 0.8H₂O*BaH₂O₂ / tetrahydrofuran; water / 16 h / 0 - 20 °C

2: pyridine; pyridine hydrogenfluoride / tetrahydrofuran / 0.42 h / 0 °C

3: potassium tert-butylate / tetrahydrofuran / 0.08 h / 20 °C

With pyridine; 0.8H₂O*BaH₂O₂; potassium tert-butylate; pyridine hydrogenfluoride; In tetrahydrofuran; water;
DOI:10.1039/c1cc12332g