C₃₃H₃₀⁽²⁾H₁₂N₂O₈S

Base Information

• Chemical Name: C₃₃H₃₀⁽²⁾H₁₂N₂O₈S
• CAS No.: 1256492-92-8
• Molecular Formula: C₃₃H₄₂N₂O₈S
• Molecular Weight: 638.676
• Mol file: 1256492-92-8.mol

Synonyms:C₃₃H₃₀⁽²⁾H₁₂N₂O₈S

Chemical Property of C₃₃H₃₀⁽²⁾H₁₂N₂O₈S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₃₀⁽²⁾H₁₂N₂O₈S

There total 8 articles about C₃₃H₃₀⁽²⁾H₁₂N₂O₈S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H3(2)H2ClO4S (1256492-68-8) + C26H28(2)H10N2O4 → C33H30(2)H12N2O8S (1256492-92-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.833333h;

DOI:10.1016/j.ejmech.2013.02.001

Reference yield:

(S)-N-[3-Chloro-2-oxo-1-[[4-(phenylmethoxy)phenyl]methyl]propyl]carbamic acid 1,1-dimethylethyl ester (152438-62-5) → C33H30(2)H12N2O8S (1256492-92-8)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium borodeuteride / ethanol; tetrahydrofuran / 1 h / -78 - 0 °C

2: potassium hydroxide / ethanol / 1 h / 20 °C

3: tetrahydrofuran / 48 h / 50 °C

4: triethylamine / dichloromethane / 0.83 h / 0 - 20 °C

With sodium borodeuteride; triethylamine; potassium hydroxide; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2013.02.001

Reference yield:

tert-butyl ((2S,3S)-1-(4-(benzyloxy)phenyl)-4-chloro-3-hydroxybutan-2-yl)carbamate-d1 (1256492-59-7) → C33H30(2)H12N2O8S (1256492-92-8)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxide / ethanol / 1 h / 20 °C

2: tetrahydrofuran / 48 h / 50 °C

3: triethylamine / dichloromethane / 0.83 h / 0 - 20 °C

With triethylamine; potassium hydroxide; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2013.02.001

upstream raw materials:

(S)-N-[3-Chloro-2-oxo-1-[[4-(phenylmethoxy)phenyl]methyl]propyl]carbamic acid 1,1-dimethylethyl ester

tert-butyl ((2S,3S)-1-(4-(benzyloxy)phenyl)-4-chloro-3-hydroxybutan-2-yl)carbamate-d1

tert-butyl ((S)-2-(4-(benzyloxy)phenyl)-1-((S)-oxiran-2-yl)ethyl)carbamate-d1

C₇H₄⁽²⁾H₂O₂

Downstream raw materials:

C₂₈H₂₂⁽²⁾H₁₂N₂O₆S

C₃₅H₂₅⁽²⁾H₁₇N₂O₁₀S

C₃₅H₂₈⁽²⁾H₁₄N₂O₁₀S

C₃₈H₃₂⁽²⁾H₁₄N₂O₁₀S

Refernces