(5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

Base Information

Chemical Name:(5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone
CAS No.:1394911-62-6
Molecular Formula:C₂₁H₂₀N₂O₂S
Molecular Weight:364.468
Hs Code.:

Synonyms:(5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

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Chemical Property of (5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

Chemical Property:

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Technology Process of (5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

There total 3 articles about (5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123-75-1
pyrrolidine

: C₁₇H₁₃NO₂S

: 1394911-62-6
(5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

Guidance literature:: With oxygen; In acetonitrile; at 20 ℃; for 7h; Reflux; Air atmosphere;
DOI:10.1016/j.tet.2012.07.002

Reference yield:

: 1-Phenyl-2-azido-3-(p-methoxyphenyl)-2-propen-1-on

: 1394911-62-6
(5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 2 h / 20 °C

2: acetonitrile / 4 h / 40 °C

3: oxygen / acetonitrile / 7 h / 20 °C / Reflux; Air atmosphere

With oxygen; In dichloromethane; acetonitrile; 1: Staudinger reaction / 2: aza-Wittig reaction;
DOI:10.1016/j.tet.2012.07.002

Reference yield:

: 1394911-53-5
C₂₉H₂₆NO₂P

: 1394911-62-6
(5-(4-methoxyphenyl)-2-(pyrrolidin-1-yl)thiazol-4-yl)(phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 4 h / 40 °C

2: oxygen / acetonitrile / 7 h / 20 °C / Reflux; Air atmosphere

With oxygen; In acetonitrile; 1: aza-Wittig reaction;
DOI:10.1016/j.tet.2012.07.002