1,4-Dioxaspiro[4.5]decan-8-ylmethanamine

Base Information Edit

Chemical Name:1,4-Dioxaspiro[4.5]decan-8-ylmethanamine
CAS No.:30482-25-8
Molecular Formula:C9H17NO2
Molecular Weight:171.239
Hs Code.:2932999099
European Community (EC) Number:873-779-5
DSSTox Substance ID:DTXSID30449569
Nikkaji Number:J1.362.069E
Wikidata:Q82269083
Mol file:30482-25-8.mol

Synonyms:1,4-dioxaspiro[4.5]decan-8-ylmethanamine;30482-25-8;1,4-Dioxaspiro[4.5]decane-8-methanamine;8-AMINOMETHYL-1,4-DIOXASPIRO[4.5]DECANE;1,4-Dioxa-spiro[4.5]dec-8-ylmethylamine;(1,4-Dioxaspiro[4.5]decan-8-yl)methanamine;{1,4-dioxaspiro[4.5]decan-8-yl}methanamine;1,4-Dioxaspiro[4,5]decane-8methanamine;8-(Aminomethyl)-1,4-dioxaspiro[4.5]decane;SCHEMBL442550;C-(1,4-DIOXA-SPIRO[4.5]DEC-8-YL)-METHYLAMINE;DTXSID30449569;OEBYRQFXIBUGSR-UHFFFAOYSA-N;MFCD11040608;AKOS005216750;SB36485;AS-37085;8-aminomethyl-1,4-dioxaspiro[4,5]decane;(1,4-dioxaspiro[4,5]dec-8-yl)methylamine;CS-0171567;FT-0658588;EN300-82582;1-(1,4-dioxaspiro[4.5]dec-8-yl)methanamine;A820395;1-{1,4-DIOXASPIRO[4.5]DECAN-8-YL}METHANAMINE;Z425641804;4-aminomethyl-2-cyclohexanone ethylene ketal;8-aminomethyl-1,4-dioxaspiro<4,5>decane

Suppliers and Price of 1,4-Dioxaspiro[4.5]decan-8-ylmethanamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Aminomethyl-1,4-dioxaspiro[4.5]decane
50mg
$ 95.00

Matrix Scientific
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine 95%
250mg
$ 180.00

J&W Pharmlab
1,4-Dioxa-spiro[4.5]dec-8-ylmethylamine 95%
500mg
$ 249.00

Crysdot
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine 95+%
10g
$ 1584.00

Crysdot
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine 95+%
1g
$ 426.00

Crysdot
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine 95+%
5g
$ 1036.00

Chemenu
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine 95%
5g
$ 978.00

Biosynth Carbosynth
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine
2 g
$ 636.00

Biosynth Carbosynth
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine
1 g
$ 373.75

Biosynth Carbosynth
1,4-Dioxaspiro[4.5]decan-8-ylmethanamine
250 mg
$ 125.00

Total 23 raw suppliers

Chemical Property of 1,4-Dioxaspiro[4.5]decan-8-ylmethanamine Edit

Chemical Property:

Vapor Pressure:0.007mmHg at 25°C
Refractive Index:1.505
Boiling Point:270.059 °C at 760 mmHg
PKA:10.20±0.29(Predicted)
Flash Point:126.861 °C
PSA：44.48000
Density:1.088 g/cm³
LogP:1.57870
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:171.125928785
Heavy Atom Count:12
Complexity:145

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-Aminomethyl-1,4-dioxaspiro[4.5]decane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCC1CN)OCCO2
Uses 8-Aminomethyl-1,4-dioxaspiro[4.5]decane is used to prepare brain-penetrating cathepsin S inhibitors.

Technology Process of 1,4-Dioxaspiro[4.5]decan-8-ylmethanamine

There total 10 articles about 1,4-Dioxaspiro[4.5]decan-8-ylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 69947-09-7
1,4-dioxaspiro<4.5>decane-8-carbonitrile

: 30482-25-8
(1,4-dioxa-spiro[4.5]dec-8-yl)-methyl-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 15h; Cooling with ice; Reflux;
DOI:10.1021/acs.jmedchem.1c00692