30482-24-7

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. Carboxamide compound

Explanation

It is a type of organic compound that contains a carboxamide functional group (-CONH2).
3. Spiro ring system
4. Dioxane ring

Explanation

A dioxane ring is a six-membered ring containing two oxygen atoms, which is part of the compound's structure.
5. Potential use in medicinal and pharmaceutical applications

Explanation

Due to its unique structure and potential biological activities, the compound may have applications in the development of new drugs or therapies.
6. Building block in organic synthesis

Explanation

The compound can be used as a starting material or intermediate in the synthesis of various organic compounds.
7. Health hazards

Explanation

The compound may pose health risks, and it is essential to handle it with care and follow proper safety protocols.
8. Qualified individuals and controlled laboratory setting

Explanation

Only trained and qualified individuals should work with 1,4-dioxaspiro<4,5>decane-8-carboxamide, and it should be used in a controlled laboratory environment to minimize risks.

Upstream product

• 26845-47-6 methyl 1,4-dioxaspiro[4.5]decane-8-carboxylate 
• 1336-21-6 ammonium hydroxide 
• 66500-55-8 cyclohexanone-4-carboxylic acid ethyleneacetal 

Downstream Products

• 30482-25-8 (1,4-dioxa-spiro[4.5]dec-8-yl)-methyl-amine 
• 1224948-79-1 1-(4-(4-methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)cyclohexan-cis-1,4-diol 
• 1224948-78-0 1-(4-(4-methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)cyclohexan-trans-1,4-diol 
• 1224948-80-4 1-(4-(4-methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)-4-(trifluoromethyl)cyclohexan-trans-1,4-diol 
• 1224948-81-5 1-(4-(4-methoxyphenyl)-5-(p-tolyl)thiazol-2-yl)-4-(trifluoromethyl)cyclohexan-cis-1,4-diol 

Relevant academic research and scientific papers

THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR FIBROMYALGIA

An object of the present invention is to provide a therapeutic agent or prophylactic agent which has an analgesic effect on both nociceptive pain and neuropathic pain and is effective in treatment of fibromyalgia. The present invention provides a therapeutic agent or prophylactic agent for fibromyalgia, said agent comprising as an effective ingredient a cyclohexane derivative exemplified by the formula below, or a pharmaceutically acceptable salt thereof or a prodrug thereof.

THERAPEUTIC AGENT AND PREVENTATIVE AGENT FOR ALZHEIMER'S DISEASE

An object of the present invention is to provide a therapeutic agent or prophylactic agent for Alzheimer's disease, which has an effect to inhibit or delay the progress of Alzheimer's disease and exhibits a long-lasting therapeutic effect on Alzheimer's disease even when used for a long period of time. The present invention provides a therapeutic agent or prophylactic agent for Alzheimer's disease, said agent comprising as an effective ingredient a cyclohexane derivative exemplified by the formula below, or a pharmaceutically acceptable salt thereof or a prodrug thereof.

CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

The present invention aims to provide a compound having a strong analgesic action against both nociceptive pain and neuropathic pain and having less side effects, and a medical use thereof. The present invention provides cyclohexane derivatives represented by the following compound, or pharmaceutically acceptable salts thereof or prodrugs thereof.

MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHASE INHIBITORS

This invention relates to polycyclic compounds containing two mono- and/or bicyclic rings and a basic tertiary amino group capable of forming an ammonium ion at biological pH and which reduces levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention. The compounds of this invention are described by the formula where Ar I is phenylene or naphthylene, Ar II is phenyl or naphthyl and A is 1-azabicyclo[2.2.2]octan-3-yl