Tributyl(3-methoxyphenyl)stannane

Base Information

• Chemical Name: Tributyl(3-methoxyphenyl)stannane
• CAS No.: 122439-11-6
• Molecular Formula: C19H34 O Sn
• Molecular Weight: 397.188
• Hs Code.: 2931200000
• DSSTox Substance ID: DTXSID40371605
• Mol file: 122439-11-6.mol

Synonyms:Tributyl(3-methoxyphenyl)stannane;122439-11-6;Tributyl-(3-methoxyphenyl)stannane;Stannane, tributyl(3-methoxyphenyl)-;3-Methoxy(tri-n-butylstannyl)benzene;SCHEMBL1255316;DTXSID40371605;AKOS024438363;3-Methoxy(tri-n-butylstannyl)benzene 95+%;FT-0762898

Chemical Property of Tributyl(3-methoxyphenyl)stannane

Chemical Property:

• PSA: 9.23000
• LogP: 5.75130
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 11
• Exact Mass: 398.163168
• Heavy Atom Count: 21
• Complexity: 232

Purity/Quality:

97% ^*data from raw suppliers

3-METHOXY(TRI-N-BUTYLSTANNYL)BENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC[Sn](CCCC)(CCCC)C1=CC=CC(=C1)OC

Technology Process of Tributyl(3-methoxyphenyl)stannane

There total 6 articles about Tributyl(3-methoxyphenyl)stannane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-methoxyphenyl bromide (2398-37-0) + tributyltin chloride (1461-22-9) → tributyl(3-methoxyphenyl)stannane (122439-11-6)

Guidance literature:

3-methoxyphenyl bromide; With magnesium; In tetrahydrofuran; at 20 ℃; for 1.08333h; Inert atmosphere; Reflux;

tributyltin chloride; In tetrahydrofuran; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1039/c8ob00630j

Reference yield: 86.0%

3-methoxyphenyl bromide (2398-37-0) → tributyl(3-methoxyphenyl)stannane (122439-11-6)

Guidance literature:

With magnesium; ethylene dibromide; In tetrahydrofuran; at 35 ℃; for 1h; regioselective reaction; Sonication; Inert atmosphere;

DOI:10.1016/j.jorganchem.2013.04.044

Reference yield: 77.0%

bis(tri-n-butyltin) (813-19-4) + sodium 3-methoxybenzenesulfinate → tributyl(3-methoxyphenyl)stannane (122439-11-6)

Guidance literature:

With bis(tri-t-butylphosphine)palladium⁽⁰⁾; silver carbonate; In N,N-dimethyl acetamide; at 140 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.09.065

upstream raw materials:

3-methoxyphenyl bromide

tributyltin chloride

bis(tri-n-butyltin)

O-methylresorcine

Downstream raw materials:

(3-methoxyphenyl)(4-nitrophenyl)methanone

3-methoxybenzophenone

4,3'-dimethoxybenzophenone

(4-chlorophenyl)(3-methoxyphenyl)methanone

Refernces

• 1、 Pudnika, Linda,Domraceva, Ilona,Werner, Thomas,Zalubovskis, Raivis,Grandane, Aiga. "Base-free catalytic wittig-/cross-coupling reaction sequence as short synthetic strategy for the preparation of highly functionalized arylbenzoxepinones". . p. 3545 - 3554. Retrieved 2021/07/02.
• 2、 Lian, Chang,Yue, Guanglu,Zhang, Haonan,Wei, Liyan,Liu, Danyang,Liu, Sichen,Fang, Huayi,Qiu, Di. "Synthesis of arylstannanes by palladium-catalyzed desulfitative coupling reaction of sodium arylsulfinates with distannanes". supporting information. p. 4019 - 4023. Retrieved 2018/10/04.