Carbamic acid, (2-oxo-4-pentenyl)-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, (2-oxo-4-pentenyl)-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 121505-97-3
• Molecular Formula: C₁₀H₁₇NO₃
• Molecular Weight: 199.25
• Mol file: 121505-97-3.mol

Synonyms:Carbamic acid, (2-oxo-4-pentenyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, (2-oxo-4-pentenyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, (2-oxo-4-pentenyl)-, 1,1-dimethylethyl ester (9CI)

There total 3 articles about Carbamic acid, (2-oxo-4-pentenyl)-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

allylmagnesium bromide (2622-05-1) + tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate (121505-93-9) → tert-butyl (2-oxopent-4-en-1-yl)carbamate (121505-97-3)

Guidance literature:

With methylmagnesium chloride; In tetrahydrofuran; at -15 - 20 ℃;

DOI:10.1016/S0040-4039(02)02031-2

Reference yield: 87.0%

tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate (121505-93-9) + allylmagnesium bromide (1730-25-2) → tert-butyl (2-oxopent-4-en-1-yl)carbamate (121505-97-3)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 12h; Inert atmosphere;

Reference yield:

BOC-glycine (4530-20-5) → tert-butyl (2-oxopent-4-en-1-yl)carbamate (121505-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1: DCCI

2: 54 percent / tetrahydrofuran / 4 h / -70 - -10 °C

With dicyclohexyl-carbodiimide; In tetrahydrofuran;

upstream raw materials:

tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate

allylmagnesium bromide

allylmagnesium bromide

BOC-glycine