(1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

Base Information

Chemical Name:(1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine
CAS No.:1310731-27-1
Molecular Formula:C₂₈H₂₉N₅
Molecular Weight:435.572
Hs Code.:

Synonyms:(1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

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Technology Process of (1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

There total 4 articles about (1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1428242-83-4
C₃₅H₃₅N₅O₂S

: 1310731-27-1
(1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 60 ℃; for 16h;

Reference yield:

: 1310731-26-0
1-((1S,2R,4S)-4-(dibenzylamino)-2-methylcyclopentyl)-2-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylamino)ethanone

: 1310731-27-1
(1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic anhydride; trifluoroacetic acid / acetonitrile / 42 h / 40 °C / Cooling with ice

2: sodium hydroxide / tetrahydrofuran; water / 16 h / 60 °C

With trifluoroacetic acid; trifluoroacetic anhydride; sodium hydroxide; In tetrahydrofuran; water; acetonitrile;

Reference yield:

: 1310731-25-9
(1S,2R,4S)-2-(2-methyl-4-(dibenzylamino)cyclopentyl)-dimethylsulfoxonium-2-oxo-ethylide

: 1310731-27-1
(1S,3S,4R)-N,N-dibenzyl-3-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-4-methylcyclopentanamine

Guidance literature:: Multi-step reaction with 3 steps

1: bis(1,5-cyclooctadiene)diiridium(I) dichloride / chloroform / 68 h / 70 °C / Inert atmosphere

2: trifluoroacetic anhydride; trifluoroacetic acid / acetonitrile / 42 h / 40 °C / Cooling with ice

3: sodium hydroxide / tetrahydrofuran; water / 16 h / 60 °C

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; trifluoroacetic acid; trifluoroacetic anhydride; sodium hydroxide; In tetrahydrofuran; chloroform; water; acetonitrile;